Short Wave

From Scientific Exile To Gene Editing Pioneer


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Gene editing was a new idea in the mid-1970s. So when Harvard and MIT planned new research in recombinant DNA, alarm bells went off. "People were worried about a 'Frankengene,'" says Lydia Villa-Komaroff, then a freshly minted PhD. Amidst a political circus, the city of Cambridge, Massachusetts banned research into recombinant DNA, forcing scientists like Villa-Komaroff into exile. But that turned out to be just the prelude to a breakthrough. In this episode, Dr. Villa-Komaroff tells Emily Kwong the story of overcoming the skeptics and coaxing bacteria into producing insulin for humans.

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