As we eat, our gastrointestinal (GI) system releases a host of both local and distant regulators to control the process of digestion. We will begin with the primary hormones, then cover some of the secondary hormones, and lastly discuss how our body senses its intraluminal contents and then subsequently integrates all of the various stimuli it receives.

After listening to this AudioBrick, you should be able to:

Identify the location, cell type, release stimulus to the endocrine cells, and function of the major gastrointestinal (GI) hormones secretin, cholecystokinin (CCK), gastrin, vasoactive intestinal polypeptide (VIP).

Describe in brief the release stimulus and function of the GI regulatory peptides bombesin, GLP-1, GLP-2, ghrelin, leptin, motilin, somatostatin, and gastric inhibitory polypeptide (GIP).

Understand how the physical and chemical compositions of luminal contents are sensed and the hormonal responses that then occur.

Outline how GI cells integrate multiple regulatory inputs from hormonal and neural inputs to control function.

You can also check out the original brick on Gastrointestinal Regulatory Substances  from our Gastrointestinal collection, which is available for free.

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You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.

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