Genetics (Audio)

Scott Kelly spent a year in the International Space Station while his identical twin Mark Kelly was on earth. UC San Diego and many institutions studied the mental, cardiovascular, immune, genetic, muscular, microbial, bone, and eye changes in both twins to see the effects of long-term space travel. Changes were troubling, so NASA plans several more long-term space flights that will focus on genetic changes, bone loss, loss of vision, brain swelling, and Nutrition. Michael G. Ziegler, MD, is Professor of Medicine Emeritus at UCSD. He has studied astronaut health since 1978. He chaired NASA’s yearly cardiovascular reviews, helped devise current astronaut protocols, and studied physiologic and genomic changes during the Year in Space study.   Series: "Osher UC San Diego Distinguished Lecture Series" [Health and Medicine] [Science] [Show ID: 35085]

A team of engineers at UC Berkeley and the Keck Graduate Institute (KGI) of The Claremont Colleges combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes. The device, dubbed CRISPR-Chip, could be used to rapidly diagnose genetic diseases or to evaluate the accuracy of gene-editing techniques. The team used the device to identify genetic mutations in DNA samples from Duchenne muscular dystrophy patients. Series: "UC Berkeley News" [Health and Medicine] [Show ID: 35130]

This CARTA symposium focuses on the contributions of scientists and scholars of anthropogeny who live and work in Africa. Himla Soodyall, National Health Laboratory Service (Johannesburg); University of the Witwatersrand, explores the links between the historical and genetic narrative of populations in southern Africa.

Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 34986]

Ultrasounds are one of the many tools available to help you have a healthy pregnancy. They can be used to monitor fetal growth, estimate risks for genetic disorders, discover the gender of your baby, and much more. Dr. Julia Cormano discusses the different types of ultrasounds that may be done during your pregnancy and how this technology can provide a unique view of your baby's development. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 34773]

You have the option to screen for a number of genetic disorders in pregnancy. How are these tests performed and what can be discovered? Dr. Julia Cormano explains the difference between screening and diagnostic testing, what can be learned from a blood test, as well what to expect from chorionic villus sampling and amniocentesis. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 33874]

Tony Wynshaw-Boris, MD, PhD describes his lab's efforts to use mouse and IPSC models to find commonalities that give insight into the complex disorder of autism. Series: "Autism Programs for Medical Professionals" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 34977]

Genetic testing has become a routine part of pregnancy, but what do the results mean? Genetic counselors play a valuable role in interpreting your results and guiding you through the process of what to do with that information. Dr. Julia Cormano sits down with genetic counselors Christina Brock and Andrea Procko to find out how they support patients throughout pregnancy. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 34915]

The search for human-specific genome changes underlying the unique neocortex expansion found only in the human brain. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 32971]

Khalid Shah, MS, PhD discusses translating biological therapies into clinical care. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 34912]

Can scientists genetically engineer mosquitos to eliminate malaria? Professor Ethan Bier from UC San Diego believes they can. In this talk at the Osher Lifelong Learning Institute, he discusses various ways in which self-copying—or active—genetic elements can be used to bias inheritance of beneficial characteristics. Such active genetic elements can be used to confer resistance to transmission of pathogens, re-sensitize pesticide-resistant insect pests and disease-vector populations to insecticides, restore natural ecosystems, or combine multiple favorable traits to create animal models for human disease or optimized agricultural strains of plants. Series: "Osher UC San Diego Distinguished Lecture Series" [Science] [Show ID: 34753]