Despite advances in prevention, rapid diagnosis and treatment and

being a focus disease for the Millenium Development Goals, malaria

continues to claim an unacceptable number of lives.

The first experiments in malaria vaccinology date back several

decades. There was excitement on the release of the Colombian Spf66

vaccine in the 1980s but this was followed by disappointed as the

trial results did not translate into the expected effictiveness on the

ground. Since then, molecular advances have seen a new wave of

candidate vaccines including the RTS.

In this podcast, ADC's global health editor Nick Brown discusses with Lorenz von Seidlein, an eminent malariologist at Menzies School of Health Research, Australia, the reasons why an effective vaccine has proved so elusive, the range of new candidates and hopes for the future.

Read Lorenz's full article here: http://adc.bmj.com/content/98/12/981.full