Putin has approved changes to Russia’s nuclear doctrine. We speak to political editor, Nicholas Cecil. Patient blood could repair bones, Professor Alvaro Mata of pharmacy and chemical engineering, at the University of Nottingham, explains the study. Plus, The Game Awards 2024 with culture writer, and tv and games editor, Vicky Jessop.

Also in this show:

• UK snow latest: the “first taste of winter” – Met Office
• Move over Gladiator 2, London’s Hidden Gems: Roman Amphitheatre.

Read the article here or watch the video here.

• Police warn 4x4 drivers to stop chasing escaped emu

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