Healio Minute

In this edition, we look at how testosterone and exercise affect older women with hip fracture, how vitamin C may be an effective alternative to glucocorticoids and more.

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Function not improved with testosterone plus exercise after hip fracture in older women

Vitamin C may be effective alternative to glucocorticoids in total hip arthroplasty

Hip resurfacing may be effective for younger, active men with osteoarthritis

Robotic-assisted THA may reduce opioid requirements vs. manual, computer-assisted THA

One-stage exchange may provide alternative for chronic PJI

References:

Binder EF, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.10512.

Expert Submission

Giannakis P, et al. e-Poster 6833. Presented at: Anesthesiology and Acute Pain Medicine Meeting; May 1-3, 2025; Orlando.

Jiang W, et al. J Bone Joint Surg Am. 2025;doi:10.2106/JBJS.24.01080.

Zuke WA, et al. J Bone Joint Surg Am. 2025;doi:10.2106/JBJS.24.00926.

In this edition, light physical activity linked to lower cancer risk, lung lesion diagnostic yield from bronchoscopy and more.

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'Every bit of movement counts': Even light physical activity linked to lower cancer risk

Robotic, electromagnetic navigation bronchoscopy have similar lung lesion diagnostic yield

Women with history of adverse pregnancy outcomes face elevated risk for future COPD

Long-term blood pressure lowering does not appear to impact risk for new-onset cancer

Most patients with advanced cancer do not undergo next-generation sequencing testing

References:

Chehade CH, et al. Abstract 11014. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago.

Paez R, et al. Am J Respir Crit Care Med. 2025;doi:10.1164/rccm.202409-1846OC.

Shreves AH, et al. Br J Sports Med. 2025;doi:10.1136/bjsports-2024-109360.

Sridhar S, et al. Adverse pregnancy outcomes and future maternal risk of developing COPD: An analysis of the Women's Health Initiative. Presented at: American Thoracic Society International Conference; May 16-21, 2025; San Francisco.

Zazarzadeh M, et al. JACC CardioOncol. 2025;doi:10.1016/j.jaccao.2025.03.005.

In this edition, IBD social risks linked to unplanned ED use, anal cancer screening for men with HIV may cut deaths by 65% and more.

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Nearly two-thirds of adults with IBD experience social risks linked to unplanned ED use

Anal cancer screening at age 35 for gay, bisexual men with HIV may cut deaths by 65%

'Not just a physical issue': CRC linked to adverse sexual health outcomes among women

'We need to take ownership': ACG guideline urges preventive care in IBD management

Managing gut dysbiosis may offer 'therapeutic window' for severe alcoholic hepatitis

References:

Deshmukh AA, et al. Ann Intern Med. 2025;doi:10.7326/ANNALS-24-01426.

Farraye FA, et al. Am J Gastroenterol. 2025;doi:10.14309/ajg.0000000000003541.

Kim S, et al. Clin Gastroenterol Hepatol. 2025;doi:10.1016/j.cgh.2025.03.031.

Oveisi N, et al. J Natl Cancer Inst. 2025;doi:10.1093/jnci/djaf120.

Vaithiyam V, et al. Cureus. 2025;doi:10.7759/cureus.85516.

In this edition, we look at knee replacement survivorship, how DEI statements may lead to more women in sports medicine programs and more.

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Public DEI statements may lead to more women faculty, fellows in sports medicine programs

Knee replacements have high long-term survivorship in young patients

Aragonite-based scaffold yielded similar outcomes between men, women with chondral defects

Platelet-rich plasma may be inferior to corticosteroid injections for knee osteoarthritis

Bioinductive collagen implant had similar outcomes as suture anchors in rotator cuff tears

References:

Hurley ET, et al. Clinical outcomes of bioinductive collagen implants for high-grade partial rotator cuff tears. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C

Kon E, et al. Female patients report comparable results to males after the implantation of an aragonite scaffold. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C.

Pai J, et al. Diversity, equity and inclusion initiatives and faculty roles in orthopedic sports fellowship. Presented at: Arthroscopy Association of North America Annual Meeting; May 8-10, 2025; Washington, D.C.

Swartz GN, et al. Poster e251. Presented at: American Academy of Orthopaedic Surgeons Annual Meeting; March 10-14, 2025; San Diego.

Weinblatt AI, et al. Paper 416. Presented at: American Academy of Orthopaedic Surgeons Annual Meeting; March 10-14, 2025; San Diego.

In this edition, DREAM program 'better than anything' available, maintenance regimen a potential new standard and more.

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DREAM program 'better than anything' available for patients with advanced lung cancer

Maintenance regimen a potential new standard in extensive-stage small cell lung cancer

'It can save their lives': Annual lung cancer screening improves cancer detection rate

Assay predicts adjuvant chemotherapy benefit in early-stage non-small cell lung cancer

High environmental burden has associations with incidence of multiple cancer types

References:

Kamarei AMA, et al. Abstract 11009. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago.

Kim RY, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.0942.

Paz-Ares LG, et al. Abstract #8006. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago.

Press Release

Spigel DR, et al. Abstract LBA8027. Presented at: ASCO Annual Meeting; May 30-June 3, 2025; Chicago.

In this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be 'new standard' in advanced lung cancer and more.

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Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970

First-line combination should be 'new standard' in advanced lung cancer

Only 1 in 5 people treated with immune checkpoint inhibitors respond to therapy

'It can save their lives': Annual lung cancer screening improves cancer detection rate

'Are we giving false hope?': Few hospitalized people with cancer benefit from immunotherapy

References:

Haslam A, et al. Int J Cancer. 2025;doi:10.1002/ijc.35347.

Islami F, et al. CA Cancer J Clin. 2025;doi:10.3322/caac.70005.

Kim RY, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.0942.

Riaz F, et al. JCO Oncol Pract. 2025;doi:10.1200/OP-24-00788.

Yang JCH, et al. Amivantamab plus lazertinib vs osimertinib in first-line EGFR-mutant advanced NSCLC. Presented at: European Lung Cancer Congress; March 26-29, 2025; Paris.

In this edition, reduction efforts prevent 3.8 million lung cancer deaths since 1970, first-line combination should be 'new standard' in advanced lung cancer and more.

Read the full coverage here:

Smoking cessation, reduction efforts prevent 3.8 million lung cancer deaths since 1970

First-line combination should be 'new standard' in advanced lung cancer

Only 1 in 5 people treated with immune checkpoint inhibitors respond to therapy

'It can save their lives': Annual lung cancer screening improves cancer detection rate

'Are we giving false hope?': Few hospitalized people with cancer benefit from immunotherapy

References:

Haslam A, et al. Int J Cancer. 2025;doi:10.1002/ijc.35347.

Islami F, et al. CA Cancer J Clin. 2025;doi:10.3322/caac.70005.

Kim RY, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.0942.

Riaz F, et al. JCO Oncol Pract. 2025;doi:10.1200/OP-24-00788.

Yang JCH, et al. Amivantamab plus lazertinib vs osimertinib in first-line EGFR-mutant advanced NSCLC. Presented at: European Lung Cancer Congress; March 26-29, 2025; Paris.

In this edition, sick food service workers top driver of viral foodborne outbreaks in US, no weight loss benefit with semaglutide before bariatric surgery and more.

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Sick food service workers remain top driver of viral foodborne outbreaks in US

'We have work to do': No weight loss benefit with semaglutide before bariatric surgery

Mailed FIT outreach program boosts colorectal cancer screening in rural areas

'Distinct viral exposure patterns' found in patients with Crohn's years before diagnosis

Mortality, dropout risk higher on liver transplant waitlist in low-density areas

References:

Coronado GD, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.0928.

Holst MM, et al. MMWR Surveill Summ. 2025;doi:10.15585/mmwr.ss7401a1.

Mathur V, et al. JAMA Surg. 2025;doi:10.1001/jamasurg.2025.0001.

Nandy A, et al. Gastroenterology. 2025;doi:10.1053/j.gastro.2025.01.247

Tanaka T, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.1759.

In this edition, recurrence-free survival estimates in less advanced lung cancer, bronchoscopy-guided microwave ablation safe in lung abnormality and more.

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Recurrence-free survival estimates after surgery higher in less advanced lung cancer

Electromagnetic navigation bronchoscopy-guided microwave ablation safe in lung abnormality

High prevalence of atherosclerosis detected in patients entering lung cancer therapy

Wood dust exposure negatively impacts lung function in carpenters

40% of people treated with chemotherapy develop persistent, severe nerve pain

References:

D'Souza RS, et al. Reg Anesth Pain Med. 2025;doi:10.1136/rapm-2024-106229.

Elfatih NM, et al. BMC Pulm Med. 2025;doi:10.1186/s12890-025-03535-x.

Malozzi C. Implementation science (application of research into practice/policy). Presented at: American College of Cardiology's Advancing the Cardiovascular Care of the Oncology Patient course; Feb. 14-16, 2025; Washington, D.C.

Rajaram R, et al. CHEST. 2023;doi:10.1016/j.chest.2023.11.042.

Wang S, et al. J Thorac Dis. 2024;doi:10.21037/jtd-24-1052.

In this edition, robotic-assisted bronchoscopy a 'game changer', global mortality related to tobacco drops, particulate matter rises and more.

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Robotic-assisted bronchoscopy a 'game changer' in early diagnosis of lung cancer

Global lung cancer mortality related to tobacco drops, particulate matter rises in 2019

Osimertinib linked to more therapy-related cardiac events than other TKIs for NSCLC

Survival better with lobectomy vs. wedge resection in early stage lung cancer

Zenocutuzumab exhibits efficacy in NRG1 fusion-positive cancers

References:

Expert Submission

Jani CT, et al. eClinicalMedicine. 2025;doi:10.1016/j.eclinm.2024.103033.

Lin CY, et al. JAMA Netw Open. 2024;doi:10.1001/jamanetworkopen.2024.48364.

Schram AM, et al. N Engl J Med. 2025;doi:10.1056/NEJMoa2405008.

Seder C. Anatomic lung resection is associated with improved survival compared with wedge resection for stage IA non-small cell lung cancer. Presented at: 2025 Society of Thoracic Surgeons Annual Meeting; Jan. 24-26; Los Angeles.