Healio Minute

In this edition, immunotherapy in advanced lung cancer, updates in EGFR-mutated lung cancer and more. Read the full coverage here:

VIDEO: Immunotherapy in advanced lung cancer among highlights from ESMO 2025

VIDEO: Updates in EGFR-mutated lung cancer from ESMO 2025

VIDEO: DeLLphi-303 results show 'major jump in survival' for SCLC patients Emphysema found during lung cancer screening raises risk for mortality Q&A: More nonsmokers developing lung cancer due to radon exposure, air pollution References

· González Gutiérrez J, et al. Radiology. 2025;doi:10.1148/radiol.250949.

· Healio Interviews

· Healio Interviews

· Healio Interviews

· Paulson KG, et al. Abstract OA13.01. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

In this edition, we look at robotic-assisted surgery, dislocation risk in fixed-bearing THA and more.

Read the full coverage here:

Higher head-to-cup ratio, robotic-assisted surgery may lower dislocation rate after THA

Fully maximizing bearing diameter may reduce dislocation risk in fixed-bearing THA

How may GLP-1s impact nutrition prior to orthopedic surgery?

Medicare contractors propose coverage restriction of peripheral nerve block procedures

Physician content on TikTok may guide patient education

References:

Expert submission

Healio Interviews

Healio Interviews

Kobayashi JK, et al. Paper 54. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Wang E, et al. Maximizing bearing diameter markedly lowers dislocations in primary total hip arthroplasty. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

In this edition, FDA warns complications following radiofrequency microneedling device use, chronic hand eczema considered "common" disease, and more. Read the full coverage here:

Q&A: FDA warns of radiofrequency microneedling risks; here's what to know

Chronic hand eczema now considered a 'common' skin disease in US

'Unproven' topical estrogens for the face may bring some risks

FDA approves Restylane Lyft to treat receding chin

References

Chovatiya R, et al. Prevalence of self-reported physician diagnosis of chronic hand eczema in adults: A cross-sectional study of more than 10,000 participants in the general population – Results from the CHECK study in the United States. Presented at: Fall Clinical Dermatology Conference; Oct. 23-26, 2025; Las Vegas.

Farkas E, et al J Am Acad Dermatol. 2025;doi:10.1016/j.jaad.2025.08.050.

Healio Interviews

Press Release

In this edition, we look at rehabilitation protocols, how AI can help patients with total knee arthroplasty, synthetic THC and more.

Read the full coverage here:

'Quiet knee' rehabilitation protocol may reduce opioid exposure after TKA

AI-enabled decision aid may improve TKA decision-making

Synthetic THC may not reduce opioid intake after TKA

Lorecivivint yields 'meaningful' improvements in knee osteoarthritis at 1 year

Corticosteroid injections yield 'disappointing' response in knee osteoarthritis

References:

Baker J. Abstract 2624. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago.

Bhatti P, et al. Poster 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Jayakumar P, et al. Paper 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Jennings JM, et al. Paper 10. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

Yazici Y. Abstract 2626. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago.

In this edition, Congress reintroduces the Safe Step Act, an expert expresses doubt about the benefits of TrumpRx and more. Read the full coverage here:

Congress reintroduces Safe Step Act to amend step therapy policies

Q&A: TrumpRx, Pfizer deal sidestep health insurance companies

Complete hair regrowth for some with alopecia after 3-year ritlecitinib treatment

Waterproof bandages 'reasonable alternative' to petroleum-based wound care

References

· Bell MC, et al JAMA Dermatol. 2026;doi:10.1001/jamadermatol.2025.4051.

· Healio Interviews

· King B, et al. Abstract #LBA-335. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

In this edition, increased lung cancer screening improving outcomes, overall survival data from FLAURA2 trial and more. Read the full coverage here:

Increased lung cancer screening improving outcomes, but rates 'still too low'

VIDEO: Overall survival data from FLAURA2 trial presented at WCLC

Updated NCCN guidelines on NSCLC put spotlight on biomarker testing 'Never too late': Smoking cessation after cancer diagnosis can extend survival New treatments worsened income-based survival disparities for lung cancer, melanoma References

· American Lung Association 2025 State of Lung Cancer.

· Khor S, et al. JCO Oncol Adv. 2025;doi:10.1200/OA-25-00026.

· National Comprehensive Cancer Network.

· Planchard D, et al. Abstract PL02.06. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

· Tohmasi S, et al. J Natl Compr Canc Netw. 2025;doi:10.6004/jnccn.2025.7059.

In this edition, we look at the first FDA approval of an oral therapy for chronic spontaneous urticaria, and more.

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FDA approves first oral therapy for chronic spontaneous urticaria

Denifanstat safe, effective in acne vulgaris treatment

FDA approves Zoryve cream 0.05% for pediatric atopic dermatitis

The 'Zoom boom' effect: Post-pandemic cost concerns for facial cosmetic procedures

References:

F Xiang, et al. Abstract #LBA-213. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

Pecora V, et al. J Drugs Dermatol. 2025;doi:10.36849/JDD.9102.

Press Release

Press Release

In this edition, we look at how AI can help patients with total joint arthroplasty, the impact of opioid use on in-hospital sleep and more.

Read the full coverage here:

Custom-tailored AI platform may be feasible for addressing patient questions before TJA

Opioid use may negatively affect in-hospital sleep, orthopedic trauma outcomes

Polymicrobial infection may predict septic long bone nonunion repair reoperation

Patients recognize importance of nutrition after surgery, need help with implementation

GLP-1s may offer a 'protective effect' in shoulder surgery for patients with diabetes

References:

Barth K, et al. Paper 63. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Martiono JA, et al. Paper 1. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego.

Rizk AA, et al. Paper 4. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego.

Schenker ML, et al. Paper 65. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Zepeda KE, et al. Poster 13. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

In this edition we look at hip fracture surgery delays, how homelessness affects hip surgery outcomes and more.

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Hip fracture surgery delay may increase mortality risk

Homelessness may be a predictor of poor outcomes following hip fracture surgery

Biological age, age acceleration may predict 1-year mortality after geriatric hip fracture

Hip resurfacing device had low all-cause revision rate at 8-year follow-up

Group cycling program leads to 'meaningful benefit' in hip osteoarthritis

References:

Cobb JP. Paper 11. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct 23-26, 2025; Dallas.

Healio interviews

Hoveidaei AH, et al. Paper 7. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

King SW, et al. Hip fracture surgery delayed by operating room capacity is an independent risk factor for 120-day mortality. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Randall Z, et al. Paper 2. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

In this edition, FDA approves golimumab for pediatric ulcerative colitis, hospital affiliation linked to higher-cost care and more. Read the full coverage here:

FDA approves golimumab for pediatric ulcerative colitis

'Tremendous implications': Hospital affiliation linked to higher-cost care

'Set a 2-TikTok limit': Smartphone use on toilet linked to higher risk for hemorrhoids

APPs step up to fill GI care gaps, but scant on-the-job training fuels own burnout

Rideshare 'potentially scalable intervention' to improve colonoscopy after abnormal FIT

References:

Expert Submission

Issaka RB, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.30515.

Kapoor DA et al. J Mark Access Health Policy. 2025;doi:10.3390/jmahp13030036.

Press Release

Ramprasad C, et al. PLoS One. 2025;doi:10.1371/journal.pone.0329983.