In this edition, Congress reintroduces the Safe Step Act, an expert expresses doubt about the benefits of TrumpRx and more. Read the full coverage here:

Congress reintroduces Safe Step Act to amend step therapy policies

Q&A: TrumpRx, Pfizer deal sidestep health insurance companies

Complete hair regrowth for some with alopecia after 3-year ritlecitinib treatment

Waterproof bandages 'reasonable alternative' to petroleum-based wound care

References

· Bell MC, et al JAMA Dermatol. 2026;doi:10.1001/jamadermatol.2025.4051.

· Healio Interviews

· King B, et al. Abstract #LBA-335. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

In this edition, increased lung cancer screening improving outcomes, overall survival data from FLAURA2 trial and more. Read the full coverage here:

Increased lung cancer screening improving outcomes, but rates 'still too low'

VIDEO: Overall survival data from FLAURA2 trial presented at WCLC

Updated NCCN guidelines on NSCLC put spotlight on biomarker testing 'Never too late': Smoking cessation after cancer diagnosis can extend survival New treatments worsened income-based survival disparities for lung cancer, melanoma References

· American Lung Association 2025 State of Lung Cancer.

· Khor S, et al. JCO Oncol Adv. 2025;doi:10.1200/OA-25-00026.

· National Comprehensive Cancer Network.

· Planchard D, et al. Abstract PL02.06. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

· Tohmasi S, et al. J Natl Compr Canc Netw. 2025;doi:10.6004/jnccn.2025.7059.

In this edition, we look at the first FDA approval of an oral therapy for chronic spontaneous urticaria, and more.

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FDA approves first oral therapy for chronic spontaneous urticaria

Denifanstat safe, effective in acne vulgaris treatment

FDA approves Zoryve cream 0.05% for pediatric atopic dermatitis

The 'Zoom boom' effect: Post-pandemic cost concerns for facial cosmetic procedures

References:

F Xiang, et al. Abstract #LBA-213. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.

Pecora V, et al. J Drugs Dermatol. 2025;doi:10.36849/JDD.9102.

Press Release

Press Release

In this edition, we look at how AI can help patients with total joint arthroplasty, the impact of opioid use on in-hospital sleep and more.

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Custom-tailored AI platform may be feasible for addressing patient questions before TJA

Opioid use may negatively affect in-hospital sleep, orthopedic trauma outcomes

Polymicrobial infection may predict septic long bone nonunion repair reoperation

Patients recognize importance of nutrition after surgery, need help with implementation

GLP-1s may offer a 'protective effect' in shoulder surgery for patients with diabetes

References:

Barth K, et al. Paper 63. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Martiono JA, et al. Paper 1. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego.

Rizk AA, et al. Paper 4. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego.

Schenker ML, et al. Paper 65. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Zepeda KE, et al. Poster 13. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.

In this edition we look at hip fracture surgery delays, how homelessness affects hip surgery outcomes and more.

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Hip fracture surgery delay may increase mortality risk

Homelessness may be a predictor of poor outcomes following hip fracture surgery

Biological age, age acceleration may predict 1-year mortality after geriatric hip fracture

Hip resurfacing device had low all-cause revision rate at 8-year follow-up

Group cycling program leads to 'meaningful benefit' in hip osteoarthritis

References:

Cobb JP. Paper 11. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct 23-26, 2025; Dallas.

Healio interviews

Hoveidaei AH, et al. Paper 7. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

King SW, et al. Hip fracture surgery delayed by operating room capacity is an independent risk factor for 120-day mortality. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

Randall Z, et al. Paper 2. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.

In this edition, FDA approves golimumab for pediatric ulcerative colitis, hospital affiliation linked to higher-cost care and more. Read the full coverage here:

FDA approves golimumab for pediatric ulcerative colitis

'Tremendous implications': Hospital affiliation linked to higher-cost care

'Set a 2-TikTok limit': Smartphone use on toilet linked to higher risk for hemorrhoids

APPs step up to fill GI care gaps, but scant on-the-job training fuels own burnout

Rideshare 'potentially scalable intervention' to improve colonoscopy after abnormal FIT

References:

Expert Submission

Issaka RB, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.30515.

Kapoor DA et al. J Mark Access Health Policy. 2025;doi:10.3390/jmahp13030036.

Press Release

Ramprasad C, et al. PLoS One. 2025;doi:10.1371/journal.pone.0329983.

In this edition, radiation is a 'strong alternative' for surgery, FDA approves combination therapy for small cell lung cancer and more.

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Radiation a 'strong alternative' to surgery for early-stage lung cancer

FDA approves lurbinectedin, atezolizumab combination for small cell lung cancer

Diagnostic yield high with robotic-assisted bronchoscopy in peripheral lung lesions

Machine learning model predicts urgent care visits during lung cancer treatment

Evidence is 'clear': Medicaid expansion significantly improves long-term cancer survival

References:

Gonzalez BD, et al. JCO Clin Cancer Inform. 2025;doi:10.1200/CCI-24-00315.

Kleber T, et al. Abstract 268. Presented at: ASTRO Annual Meeting; Sept. 27-Oct. 1, 2025; San Francisco.

Press Release

Schafer EJ, et al. Cancer Discov. 2025;doi:10.1158/2159-8290.CD-25-1244.

Steinack C, et al. OA1178: Robotic-assisted bronchoscopy with integrated cone-beam CT vs. conventional bronchoscopy for diagnosing peripheral pulmonary lesions: An open-label randomized controlled trial. Presented at: European Respiratory Society International Congress; Sept. 27-Oct. 1, 2025; Amsterdam.

In this edition, bioinductive implants for ACL reconstruction, osteochondral defects treatments and more.

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ACL reconstruction with reinforced bioinductive implant may yield favorable outcomes

Multiplug, single-plug techniques had comparable outcomes for osteochondral defects

MRI-based clinical prediction model identified risk factors for patellar instability

New technology, cost strategies continue to move robotic-assisted surgery forward

Physician referral to physical therapy underutilized for patients with knee osteoarthritis

References:

Healio Interviews

Khoja SS, et al. Arthritis Care Res. 2025;doi:10.1002/acr.25630.

McMillan S, et al. Surg Technol Int. 2025;doi:10.52198/25.STI.45.OS1888.

Mufti YN, et al. Am J Sports Med. 2025;doi:10.1177/03635465251352172.

Nukala V, et al. Arthrosc Sports Med Rehabil. 2025;doi:10.1016/j.asmr.2025.101159.

In this edition, we look at AI bias, nonsurgical biologic therapies and more.

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'Math, not magic': Identify and combat bias in AI

Orthobiologics: Commit to evidence-based practice, foster cautious optimism

TJR indications expand, making it a young man's game

Successful management of PJI occurred in about 50% of patients

Risks of anteromedial tibial tubercle transfer are minimal and the benefits great

References:

Expert Submission

Healio Interviews

Higuera Rueda C, et al. Paper 1409. Presented at: Musculoskeletal Infection Society Annual Meeting; Aug. 1-2, 2025; Jersey City, N.J.

Engagement Time: 18 minutes

In this edition, FDA approves subcutaneous chemotherapy for solid tumors, improvements to shared decision-making and more.

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FDA approves Hernexeos as first oral therapy for NSCLC with HER2 mutations

Communication, knowledge critical to improve shared decision-making for lung cancer

Detection of ctDNA could help determine use of immunotherapy for small cell lung cancer

Subcutaneous amivantamab plus lazertinib produces similar results to IV regimen in NSCLC

Lung cancer screening guidance needed for certain never-smokers

References:

Bi N, et al. Abstract 2034. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

Press Release

Scott SC, et al. Abstract 1798. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

Shum E, et al. Abstract 2172. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.

Villalon D, et al. Abstract 2368. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.