In the final episode of our podcast, Bidisha takes us on a journey through the highest of highs, from nightclubbing and the ecstasies of religion and drugs, to mania.

Artist Harold Offeh shares his personal take on the connections between movement, music and bodies.

Annie Macmanus ('DJ Annie Mac') speaks about the power of nightclubbing, how ecstasy and dance music go hand in hand and how she has managed to maintain her sense of euphoria and delight over the last couple of years.

From taking MDMA in the 80s to the work of a religious professional, the vicar, musician and radio presenter Richard Coles reflects on his adventures with both chemical and religious ecstasy.

Philosopher Jules Evans and drug science expert David Nutt talk about how people have sought to lose control throughout history, and how psychedelics are being trialled to relieve hard-to-treat cases of depression.

Finally, Bidisha asks, can you have too much of a good thing? Psychologist and writer Kay Redfield Jamison talks about her patients'—and her own—experiences of mania as part of bipolar disorder.

Presented by Bidisha Produced by Debbie Kilbride Sound design by Micky Curling Music by Sola Researched by Priya Jay Executive producer Emily Wiles