Humanities (Video)

Cerebral organoids, also known as mini-brains, are tridimensional self-organized structures derived from stem cells that resemble the early stages of the human embryonic brain. This new tool allows researchers to explore fundamental neurodevelopmental steps otherwise inaccessible in utero experimentally. Alysson Muotri, UC San Diego Stem Cell Program, explains how mini brains are generated in his lab and how this strategy can create novel therapeutical insights on neurogenetic disorders, such as autism. He also describes the use of mini-brains to explore the uniqueness of the human brain compared to other extinct species, such as the Neanderthals. Limitations and ethical concerns surrounding this exciting technology are also discussed. Series: "Exploring Ethics" [Humanities] [Science] [Show ID: 33715]

Organoides cerebrais, também conhecidos como minicérebros, são estruturas auto-organizadas tridimensionais derivadas de células-tronco que se assemelham aos estágios iniciais do cérebro embrionário humano. Esta nova ferramenta permite que pesquisadores explorem etapas fundamentais do neurodesenvolvimento que, experimentalmente, são inacessíveis no útero. Alysson Muotri, do Programa de Células-tronco da UC San Diego (Universidade da Califórnia San Diego), explica como minicérebros são gerados em seu laboratório e como esta estratégia pode criar novos insights terapêuticos sobre distúrbios neurogenéticos, como o autismo. Ele também descreve o uso de minicérebros para explorar a singularidade do cérebro humano em comparação com outras espécies extintas, como os Neandertais. As limitações e as preocupações éticas que cercam esta tecnologia fascinante também são discutidas.

Series: "O Canal de Células-Tronco" [Humanities] [Science] [Spanish Language] [Show ID: 34642]

Los organoides cerebrales, también conocidos como minicerebros, son estructuras tridimensionales autoorganizadas derivadas de células madre que se asemejan a las primeras etapas del cerebro embrionario humano. Esta nueva herramienta permite a los investigadores explorar los pasos fundamentales del desarrollo neurológico inaccesibles en el útero de forma experimental. Alysson Muotri, Programa de Células Madre de la UC San Diego, explica cómo se generan los minicerebros en su laboratorio y cómo esta estrategia puede crear nuevas perspectivas terapéuticas sobre los trastornos neurogenéticos, como el autismo. También describe el uso de minicerebros para explorar la singularidad del cerebro humano en comparación con otras especies extintas, como los neandertales. También se discuten las limitaciones y las preocupaciones éticas que rodean a esta emocionante tecnología.

Series: "El Canal de Células Madre" [Humanities] [Science] [Spanish Language] [Show ID: 34643]

UCSB Script to Screen, hosted by Pollock Theater Director Matt Ryan, was invited to the 2019 Writers Guild Awards and 2019 WGA Beyond Words. On the red carpet, directors and screenwriters alike were able to reflect and shed light on the creative process of writing their vision on a page and then translating it to the screen. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 34590]

Song rights, first time directors, female comedians, and a critical intervention by Steven Spielberg all arise in this discussion between Beatles: Revolutions co-curator Joe Palladino and I Wanna Hold Your Hand (1978) writer/producer Bob Gale and lead actress Nancy Allen. The three speakers discuss the origins of this film, the screenplay structure, and the joy of a young cast/crew building a nostalgic coming-of-age story celebrating a moment of early Beatles’ fandom. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 34592]

Being okay with solitude improves your relationships. Sherry Turkle discusses identity and relationships with the following idea in mind: if you do not learn how to be alone you will only know how to be lonely. Series: "Excerpts" [Health and Medicine] [Humanities] [Show ID: 34650]

In The Lion Seeker and The Mandela Plot, two powerful novels full of raw, vividly-drawn characters, Kenneth Bonert has explored the unique and fascinating story of the Jews of South Africa. In this talk he explains why he became a novelist and the inspiration that he drew from growing up in Johannesburg. He talks about the history of his family and of the Jewish community in South Africa and reflect on his literary goals such as capturing the authentic voices of his characters and examining their moral and political struggles. Series: "Herman P. and Sophia Taubman Endowed Symposia in Jewish Studies" [Humanities] [Show ID: 34564]

Refugees and other displaced persons need a safe and secure way to store critical documents. They allow them to get work, go to school and ultimately live within a functioning society, but there hasn't always been a way to securely store and share them. UC Davis human rights professor and director, Keith David Watenpaugh, realized he and his team could fix that problem with Article 26 Backpack. Series: "UCTV Prime" [Humanities] [Show ID: 34582]

Visual storytelling and genre blending are central topics in this wide-ranging discussion between Quiet Place screenwriters Scott Beck and Bryan Woods and Pollock Theater director Matt Ryan. Beck and Woods reflect on and explain their desire to build a monster/sci-fi/horror/silent film that paid homage to classic television and cinema creators like Rod Serling, Alfred Hitchcock, and Charlie Chaplin while fashioning a new experience for contemporary viewers. Series: "Carsey-Wolf Center" [Humanities] [Show ID: 34569]

Noted tech venture capitalist Roger McNamee, an early mentor to Mark Zuckerberg, woke up to the serious damage Facebook and other social media outlets are doing to our society and set out to try to stop it. McNamee is in conversation with Jeff Light, publisher and editor of The San Diego Union-Tribune. Series: "Helen Edison Lecture Series" [Humanities] [Show ID: 34249]