IFLScience - The Big Questions

We're back! Here's what to expect this season, starting June 19, 2025.

It’s the holiday season, and what better time to gather your loved ones together and absolutely trounce them in an hours-long board game marathon?

Humans have been playing and enjoying competitive games for centuries. For this special episode of The Big Questions, host Laura Simmons sat down with Kelly Clancy, neuroscientist and physicist, and author of recent book Playing with Reality: How Games Shape Our World, to find out more about why we love competition so much, and what our long history of gameplaying together can teach us about each other – and ourselves. 

Welcome to IFLScience’s first-ever Halloween podcast special, bringing you a feature-length episode of The Big Questions as we take on the UK’s most haunted castle. We journeyed to Northumberland up by the Anglo-Scottish border to spend the night in Chillingham Castle, a place that allegedly boasts an above-average number of ghosts. We wanted to explore what attracts people to sites such as this one, even inspiring folks to gear up with a host of ghost-hunting tools and try and communicate with spirits, despite the fact we’ve yet to find any evidence for their existence.

At IFLScience, we don’t do things by halves, so we threw it all at the wall: Ouija boards, dungeon immersion, dowsing rods, spirit boxes, and just a bit of old-fashioned wandering around in the dark. We also spoke to Emeritus Professor Chris French, an expert in anomalistic psychology, and the founders of the Recreational Fear Lab to top up on the science of fear and better understand why it is the paranormal has us all in such a choke hold.

So, join IFLScience's Chris Carpineti, Dr Beccy Corkill, Rachael Funnell, and Dr Russ Moul as they journey into the unknown in this very special episode of The Big Questions.

It’s no secret that octopuses are intelligent – but are they sentient? And how is that reflected in the way that they’re treated?

Host Rachael Funnell is joined by Sy Montgomery, author of Secrets of the Octopus, and Sophika Kostyniuk, Managing Director at the Aquatic Life Institute, to discuss the evidence for octopuses’ sentience, and how that could impact the rights they’re afforded in science, agriculture, and the wider world.

Are humans done evolving – or could settling on an alien world with an environment unlike Earth’s take us on a different evolutionary trajectory?

Host Tom Hale is joined by Scott Solomon, author and professor of bioscience at Rice University, to discuss the myriad ways Homo sapiens may continue to evolve on Earth, and how future human settlements on Mars might influence our species’ evolution.   

Antibiotic resistance is a major health concern. We now have several harmful microbes that have evolved into versions unaffected by common treatments. To find new antibiotics scientists are looking further afield, including in the ocean.

Host Dr Alfredo Carpineti speaks to Dr Sam Afoullouss, a marine scientist at the University of South Florida, about the interesting chemistry found in the deep sea and its potential to be the pharmacy of the future.  

Coming soon: join IFLScience as we explore the questions nobody thought to ask but everyone wants the answers to. Get the behind-the-scenes conversations from CURIOUS magazine’s We Have Questions interviews, as we hunt down the experts to answer some of science’s stranger questions.

Where do baby dinosaurs come from? It’s a question that’s been burning in the collective brain of the IFLScience team for some time. In this episode, host Rachael Funnell speaks with science writer and palaeontologist Riley Black to find out what science has discovered so far about the sex lives of dinosaurs.

Our Solar System is very stable. Planets, dwarf planets, asteroids, and comets go forth in their orbit without trouble. But it won't be like this forever. The future of the solar system will have major changes in the Sun and in the planets. We spoke with astronomer Dr Jon Zink to cast our mind's eye far into the future and explore the end of the solar system.

Hinging our happiness on animals known to have a significantly shorter lifespan than our own was, in hindsight, a bad idea. Saying goodbye to a pet is an incredibly painful time in a person’s life, but what if there were a way we could help our pets live longer, better lives?

That’s exactly what Celine Halioua has been exploring as CEO and founder of Loyal, a biotech startup developing drugs to extend dog lifespan. Join host Rachael Funnell as she finds out if science really can help dogs live longer.