The Pulse by Wharton Digital Health

Isabelle Kenyon, CEO & Founder of Calibrate, on setting a new standard of care for managing metabolic health


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In this episode, I sat down with Isabelle Kenyon, CEO and Founder of Calibrate. Founded in 2020, Calibrate is a metabolic health company on a mission to change the way the world treats weight. In August of 2021, Calibrate raised a $100M Series B round led by Founders Fund and Tiger Global. Since then, the company has hired hundreds of new employees and onboarded thousands of new patients, released its first Results Report, and geared up to launch its first enterprise clients.

Isabelle and I discuss: 1) Isabelle’s own interactions with the healthcare system and why these experiences led her to commit to spending her career building a better, more consumer-centric system, 2) Why Calibrate’s emphasis on metabolic health represents a paradigm shift in how we treat weight loss and obesity, 3) Calibrate’s clinical model that combines medication, a holistic curriculum guided by synchronous 1:1 video coaching, and community, 4) The company’s plans to expand access to treatment through enterprise partnerships, and 5) Isabelle’s focus on developing both her own and her company’s self-awareness as Calibrate’s leader.

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