JACI: In Practice Editor Robert Zeiger describes the January issue, the theme of which is “Insect Sting Allergy”. Theme topics covered include venom component allergen IgE measurement, risk factors for severe sting reactions and side effects during venom immunotherapy, stinging ant anaphylaxis, mast cell disorders and hymenoptera venom-triggered anaphylaxis, large local reaction to insect stings, and shared decision making in the diagnosis and management of insect sting allergy. Dr. Zeiger then presents the Highlights of the Original Articles in the issue, which are on the topics of Insect Sting Allergy, Asthma, Drug Allergy, Eosinophilic Disorders, Food Allergy, Immunodeficiency, Mast Cell Disorders, and Urticaria