What is still possible in midlife?

Many of us reach our forties, fifties and sixties assuming that the major chapters of our lives have already been written. Careers are established, habits are set, and the opportunity for significant change may feel increasingly limited.

Jeffrey Weiss challenges that assumption.

At the age of 48, he ran his first 10-kilometre race. In the years that followed, he completed Ironman Arizona twice, finished a 72-mile ultramarathon, and embarked on a successful new chapter in his professional life that culminated in a multi-billion-dollar startup exit.

In this conversation, we explore the power of healthspan, the value of audacious goals, how fitness can transform both body and mindset, and why it's never too late to embrace a new challenge.

Jeffrey is the author of Racing Against Time: On Ironman, Ultramarathons, and the Quest for Transformation in Mid-Life.

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The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Most of us know what healthy eating looks like. The challenge is sticking to it when life gets busy, stress levels rise, and convenience wins out.

So what can we learn from the way elite athletes fuel their bodies, and from the systems that make healthy choices easier?

In this conversation, Mario Limaduran, Culinary Director for Trifecta Nutrition, explores the realities of meal planning, the role of discipline and habits, and why perfection is often the enemy of long-term success. His message is simple: healthy eating doesn't have to be complicated, but it does need to be sustainable.

Explore Trifecta Nutrition meals

Disclosure: Live Long has an affiliate relationship with Trifecta Nutrition. If you make a purchase through our link, we may receive a small commission at no additional cost to you. Your support helps fund the podcast and keeps all episodes free to access.

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

For decades, aging was seen as inevitable — a slow and irreversible decline. But a growing number of scientists now believe we may be entering a turning point, with research increasingly focused on extending not just how long we live, but how well we live.

In the documentary Forever Young, filmmaker David Donnelly — alongside producers Dr. James Johnson and Dr. Thomas Lewis — explores the rapidly evolving world of longevity science, from biological clocks and AI-driven research to the power of lifestyle, purpose, and social connection.

The film also confronts some of the field’s biggest questions: what aging actually is, whether it should be treated as a disease, and who stands to benefit if the science succeeds. In this conversation with Peter Bowes, Donnelly reflects on skepticism, scientific disagreement, and why he believes humanity may already be living through a longevity revolution.

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Learn more about Forever Young: The end of aging has just begun

Apple TV Pre-order | Official Website | Substack | Instagram | X | Facebook | YouTube | Watch the Trailer

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DISCLOSURE: This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
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Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Loneliness is increasingly being recognized not simply as a social issue, but as a major threat to public health. 

Cardiologist and behavioral medicine pioneer Dr. Alan Rozanski says the evidence is now clear: meaningful human connection influences everything from heart health to longevity and emotional resilience. 

In this conversation with Peter Bowes, he explains how social isolation affects the body biologically, why purpose and vitality matter as much as diet and exercise, and why modern life may be weakening our ability to connect. 

He also explores the difference between being alone and feeling lonely, and the complex role technology and social media now play in our relationships. Ultimately, he argues that the strongest predictor of long-term wellbeing may not simply be how long we live — but how vital and connected we feel along the way. 

-- May is National Mental Health Awareness Month, observed annually since 1949 to reduce stigma, provide support, and educate the public on mental wellness -- 

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This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

As people live longer and stay healthier for more years, retirement is being redefined. What was once seen as a relatively short closing chapter can now stretch across decades, raising deeper questions about identity, purpose and how to spend our time well. Wealth adviser Gregg Lunceford has spent years studying this transition and the gap between leaving work and living well afterwards. He argues that traditional ideas of retirement, focused mainly on financial security, miss the psychological and social role that work plays in our lives. The challenge now is not simply knowing when to stop working, but how to shape a fulfilling life beyond it.

Gregg Lunceford is a wealth advisor and researcher focused on how people navigate the transition into retirement. A Managing Director at Mesirow, he works with individuals over 50 to plan not just financially, but psychologically and socially for life beyond full-time work. Author of Exit from Work, he examines what he calls the “third age”: a potentially rich, 20-year phase shaped by reinvention, meaning, and a rethinking of what it means to live well.

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This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Weight-loss drugs that target the hormone GLP-1 have rapidly reshaped the conversation around obesity, appetite and personal responsibility. But alongside the rise of powerful synthetic injectables, researchers are also exploring whether the body’s own appetite signals can be harnessed more naturally. At the heart of the debate is a simple question: are we eating too much because of weak willpower, or because of biology? 

As new approaches emerge, the challenge is to balance effectiveness, safety and long-term sustainability in tackling one of modern health’s most persistent problems.

In this interview, Sarah Kennedy, founder of Calocurb, a New Zealand company which has developed a plant-based compound designed to naturally stimulate GLP-1, discusses the science of appetite control and how it compares to injectable drugs. 

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Try Calocurb for yourself?

Get a 10% discount HERE

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This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Where we live could be the most important factor in how long and well we live. Teri Slavik-Tsuyuki, co-chair of the Global Wellness Institute’s Wellness Communities Initiative, reveals how homes and neighborhoods influence 85% of our health outcomes—more than our genes. 

From pandemic-driven lifestyle shifts to multigenerational living, she shares how intentional design, walkable communities, and social spaces can keep us independent, active, and connected at any age. 

Discover the secrets behind wellness-focused communities and how your environment shapes your third chapter of life. 

 Additional video courtesy: Rancho Mission Viejo

This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Artificial intelligence is rapidly changing how we understand our health — not just how we feel today, but how fast we’re actually aging.

On this episode of Live Long, host Peter Bowes continues his personal experiment with Hundred, the AI-powered longevity platform that combines advanced blood testing, wearable data and personalized insights to track biological age and guide smarter health decisions.

After introducing the app in an earlier conversation, Peter reconnects with Hundred’s founder, Tyler Smith, to go deeper into the idea of a “health operating system” — essentially a personal doctor in your pocket. Together they explore how continuous testing and AI analysis could help prevent disease, spot risks earlier, and motivate lasting behavior change — while also addressing the realities of over-testing, false alarms, privacy concerns and health anxiety.

Peter also shares the results of his own first round of testing, what surprised him most, and how he’s using the data to shape his approach to longevity and healthy aging.

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JOIN HUNDRED

Optimize your healthspan and potentially lower your biological age.  Tyler and the team at HUNDRED are offering $75 in credit for add-on tests and supplements from the HUNDRED marketplace when you sign up at hundred.com/livelongpodcast

This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Was it a boozy start to the New Year? What if you could gain more clarity, energy, and better health by giving up drinking? Imagine a day when alcohol no longer dominates our thoughts—at holidays, celebrations, or even a quiet night in front of the TV. 

Alcohol-free expert James Swanwick says a cultural shift is underway, with alcohol slowly losing its grip on our social and professional lives. Even moderate drinking can quietly sap sleep, focus, and long-term wellbeing—especially for high achievers. 

In this conversation, Swanwick explains the neuroscience of addiction, why going alcohol-free is gaining momentum, and how the stigma around teetotalism is fading. He predicts that within decades, alcohol could be viewed with the same disdain as cigarettes.

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This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Pilates is more than graceful movement — it’s a strength-focused, precision-based system that builds core stability, balance, and posture for people of all ages. In the final episode of our Move for Life series Peter Bowes explores how Pilates is can help us with lifelong mobility. Originally developed as rehabilitation for dancers, Pilates uses controlled, low-repetition movements on mats and spring-based apparatus to target stabilising muscles often neglected in traditional exercise.

Ageless Workout’s Nate Wilkins and Shebah Carfagna explain how it differs from yoga and weight training and how Pilates can be used as a valuable took to nurture our longevity. 

Watch our 20-part series, Move for Life, HERE

You should consult a doctor or qualified fitness professional before beginning a new exercise program, especially if you have an existing health concerns or limited mobility.

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This podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. 

Visit our SHOP for more details: 
https://healthspan-media.com/live-long-podcast/shop/

Support the show

The Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.