In the March 2025 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss pediatric sickle cell disease and trauma-informed care. As always, you’ll also hear about the hot topics covered in Critical Decisions' regular features, including a child with difficulty walking in Clinical Pediatrics, sternoclavicular joint septic arthritis in Orthopedics and Trauma, interscalene nerve block in The Critical Procedure, intranasal topical application of tranexamic acid for atraumatic anterior epistaxis in The LLSA Literature Review, and a toddler with arm pain in The Critical Image.