Art Bell welcomes Robert Ghost Wolf, a Metis of mixed Native American and European descent, to discuss the Seven Thunders, a series of prophetic warnings compiled from elders across multiple tribes including Hopi, Lakota, Algonquin, and Cherokee. Ghost Wolf explains that these prophecies were compared at a council in the Taos Mountains in the early 1980s and describe a sequence of escalating global crises.

The first three thunders, which Ghost Wolf says have already occurred, encompass mass starvation ignored by the world, the arrival of Comet Hale-Bopp as a celestial marker, and the spread of mysterious fungal diseases linked to experimental agricultural chemicals sprayed on fields. He connects the smoke drifting from burning Mexican fields into the United States to contaminated crops carrying what he calls stealth viruses that attack at a frequency level.

Ghost Wolf reveals that the prophecies have now reached the fourth and fifth thunders, a point of no return marked by catastrophic weather patterns, devil winds exceeding 200 miles per hour, and the collapse of social, religious, and financial structures worldwide. He announces that Hopi elders feel the changes are so imminent they have agreed to speak publicly on the program for the first time.