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Atropine
Trade NameAtropen
IndicationDecreases oral and respiratory secretions, treats sinus bradycardia and heart block, treatment of bronchospasm
ActionAtropine is an anticholinergic which means that it inhibits the effects of the parasympathetic nervous system, specifically acetylcholine. This inhibition causes increase in HR, bronchodilation, decreased GI and respiratory secretions.
Therapeutic ClassAntiarrhythmic
Pharmacologic ClassAnticholinergic, antimuscarinic
Nursing Considerations• Avoid in acute hemorrhage, tachycardia, and angle closure glaucoma • Monitor patient for tachycardia and palpitations • May cause urinary retention in elderly patients • Patients may experience constipation due to slowed GI motility
Multiple Response Select N questions on the NGN require careful reading, critical thinking, and clinical judgment skills. By following these tips, you can prepare yourself for success on the NGN.
Take free NextGen practice questions at NURSING.com
Amlodipine
Trade NameNorvasc
IndicationHypertension, angina
ActionBlocks transport of calcium into muscle cells inhibiting excitation and contraction
Therapeutic ClassAntihypertensive
Pharmacologic ClassCa channel blocker
Nursing Considerations• May cause gingival hyperplasia • Grapefruit juice may increase drug level • Monitor blood pressure and pulse prior to and during therapy • Monitor intake and output • Assess for signs of CHF • Assess characteristics of angina • Instruct patient of interventions for hypertension and how to take blood pressure
amoxicillin
Trade NameMoxatag
Indicationskin infections, respiratory infections, sinusitis, endocarditis prophylaxis, lyme disease
ActionInhibits synthesis of bacterial cell wall leading to cell death.
Therapeutic Classanti-infectives, antiulcer agent
Pharmacologic Classaminopenicillins
Nursing Considerations• contraindicated with penicillin allergy • may cause seizures • assess for rash, anaphylaxis • excreted by kidneys – monitor renal labs • monitor patient for diarrhea – bloody stool should be reported immediately
The Next Generation NCLEX (NGN) matrix multiple-choice question format is designed to assess nursing students' clinical judgment skills. Here are some tips on how to answer matrix multiple-choice questions on the NGN.
Take free NextGen practice questions at NURSING.com
Visit https://nursing.com/140meds to request your free copy of "140 Must Know Meds"
Generic Name
Acetylsalicylic Acid
Trade NameAspirin
IndicationRheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis
ActionInhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases
Therapeutic ClassAntipyretics, non-opioid analgesics
Pharmacologic ClassSalicylates
Nursing Considerations• Use caution in bleeding disorders, chronic alcohol use • May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis • Increases risk for bleeding with warfarin, heparin, and clopidogrel • Increased risk for GI bleeding with NSAID use • Monitor liver function tests • Concurrent use with alcohol may increase risk for GI bleeding • Aspirin with viral infections can cause Reye's syndrome
Visit https://nursing.com/140meds to request your free copy of "140 Must Know Meds"
Generic Name
Amlodipine
Trade NameNorvasc
IndicationHypertension, angina
ActionBlocks transport of calcium into muscle cells inhibiting excitation and contraction
Therapeutic ClassAntihypertensive
Pharmacologic ClassCa channel blocker
Nursing Considerations• May cause gingival hyperplasia • Grapefruit juice may increase drug level • Monitor blood pressure and pulse prior to and during therapy • Monitor intake and output • Assess for signs of CHF • Assess characteristics of angina • Instruct patient of interventions for hypertension and how to take blood pressure
Visit https://nursing.com/140meds to request your free copy of "140 Must Know Meds"
Ampicillin
Trade NamePrincipen
IndicationSkin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia
ActionBactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death
Therapeutic ClassAnti-infective
Pharmacologic ClassAminopenicillin
Nursing Considerations• Contraindicated in penicillin allergy, use caution in renal insufficiency • May lead to seizures, diarrhea, anaphylaxis, superinfection • Assess for infection • Monitor liver function tests • Instruct patient on signs of superinfection: furry overgrowth on tongue, vaginal itching, loose and foul smelling stool • Pt should not use with oral contraceptive use.
visit https://nursing.com/140meds to request your free copy of "140 Must Know Meds"
Outline Generic NameAmitriptyline
Trade NameElavil
IndicationDepression, anxiety, insomnia, parkinson's
ActionIncreases effect of serotonin and norepinephrine in the CNS, exhibits anticholinergic effects
Therapeutic ClassAntidepressant
Pharmacologic ClassTricyclic antidepressant
Nursing Considerations• Contraindicated in MI, heart failure, QT prolongation, glaucoma • May increase risk for suicidal ideation • May cause arrhythmias, hypotension, EKG changes • May cause alterations in blood glucose levels • May lead to general sedation and lethargy • Do not use within 2 weeks of MAOIs • Instruct pt to take medication exactly as instructed • Monitor for orthostatic hypotension • May lead to photosensitivity, instruct patient to use sunscreen • May turn urine blue/green color.
Matrix multiple-response questions require students to select more than one correct answer option from a matrix table. Here's how NGN matrix multiple-response questions are scored.
Take free NextGen practice questions at NURSING.com
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