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Vancocin
Indicationlife threatening infections, sepsis
Actionbactericidal, inhibits cell wall synthesis
Therapeutic Classanti-infectives
Pharmacologic Classglycopeptides
Nursing Considerations• can cause ototoxicity, nausea, vomiting, nephrotoxicity, anaphylaxis, red-man syndrome • assess for infection • obtain culture prior to initiating therapy • monitor blood pressure • dose dependent draw serum trough levels frequently • administer over at least 60 minutes to avoid skin irritation
Lopressor, Toprol XL
Indicationtachyarrhythmias, HTN, angina, prevention of MI, heart failure management, may be used for migraine prophylaxis
Actionblocks the stimulation of beta1 receptors in the SNS, does not usually effect on beta2 receptors (cardioselective)
Therapeutic Classantianginal, antihypertensive
Pharmacologic Classbeta blocker
Nursing Considerations• monitor hemodynamics • may lead to bradycardia, pulmonary edema • use caution with MAOIs • assess I&Os and monitor for signs of CHF
Doxycycline
Indicationtreatment of infection, gonorrhea and syphilis with penicillin allergy, chronic bronchitis
Actionbacteriostatic by inhibiting protein synthesis
Therapeutic Classanti-infectives
Pharmacologic ClassTetracyclines
Nursing Considerations• use caution with liver impairment • may cause pseudomembranous colitis, diarrhea, nausea, vomiting, photosensitivity, rash • may increase effects of warfarin • assess for infection • obtain culture prior to initiating therapy • monitor renal and liver labs • instruct patient to complete entire dose
Brethine, Brethaire
Indicationasthma, COPD, preterm labor
Actionproduces smooth muscle relaxation, bronchodilator, and inhibits hypersensitivity reactions
Therapeutic Classbronchodilators
Pharmacologic Classadrenergics
tocolytics
Nursing Considerations• may cause nervousness, restlessness, tremors • beta blockers can reduce effect • assess respiratory status • monitor maternal/fetal vital signs if using for preterm labor • monitor for hypoglycemia • may cause decreased potassium level
Feosol
IndicationPrevention and treatment of iron-deficiency anemia
ActionIron is essential for hemoglobin, myoglobin and enzymes, it is transported to organs where it becomes part of iron stores
Therapeutic ClassAntianemics
Pharmacologic ClassIron supplements
Nursing Considerations• May cause seizures, hypotension, constipation, epigastric pain, diarrhea, skin staining, anaphylaxis • Assess nutritional status, bowel function • Monitor hemoglobin, hematocrit, iron levels • May cause elevated liver enzymes • Take on an empty stomach to increase absorption/vitamin c helps with absorption • Use z-track for IM injections
bronchitis, UTI, diarrhea, pneumonia, multiple types of infection
Actionbacteriacidal by preventing metabolism of folic acid
Therapeutic Classanti-infectives, antiprotozoals
Pharmacologic Classfolate antagonists, sulfonamides
Nursing Considerations• may cause renal damage, Steven Johnsons Syndrome – rash, pseudomembranous colitis, nausea, vomiting, diarrhea, rash, agranulocytosis, aplastic anemia, phlebitis • contraindicated with sulfa allergies • monitor CBC • obtain cultures prior to initiating therapy • monitor intake and output • instruct patient to complete dose • drink 8-10 glasses of water
Carafate
Indicationmanagement of GI ulcers, GI injury prevention from high dose aspirin and NSAID treatment
Actionreacts with gastric acid to form a paste that adheres to ulcer
Therapeutic Classantiulcer agent
Pharmacologic ClassGI protectant
Nursing Considerations• use caution in renal failure patients • concurrent use of antacids may decrease the effect of sucralfate – administer 30 min before or after • administer on empty stomach 1 hour before meals
Streptase
Indicationpulmonary embolism, DVT, occluded lines, arterial thrombus
Actionconverts plasminogen to plasmin which degrades fibrin clots
Therapeutic ClassThrombolytic
Pharmacologic Classplasminogen activators
Nursing Considerations• contraindicated with active bleeding, hypersensitivity, bronchospasm, intracranial hemorrhage, hypotension • begin therapy as soon as possible • monitor vital signs continuously • monitor closely for bleeding • monitor hemodynamics • avoid invasive procedures
Aldactone
Indicationpotassium loss, hypertension, edema, CHF
Actioninhibits sodium reabsorption while sparing potassium and hydrogen
Therapeutic ClassDiuretics
Pharmacologic Classpotassium sparing diuretics
Nursing Considerations• contraindicated with hyperkalemia • monitor intake and output • monitor blood pressure • monitor potassium levels and renal panel
Zoloft
Indicationmajor depressive disorder, OCD, anxiety
Actioninhibits uptake of serotonin allowing for higher quantities available within synaptic cleft
Therapeutic ClassAntidepressant
Pharmacologic ClassSSRI
Nursing Considerations• do not use with MAOIs • can cause neurolyptic malignant syndrome, suicidal thoughts, drowsiness, insomnia, diarrhea, dry mouth, tremors, serotonin syndrome, sexual dysfunction • monitor mood changes in patient • takes 1-4 weeks for therapy to be effective.
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