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Fentanyl
Trade NameSublimaze
IndicationSupplement to general anesthesia, continuous IV infusion for purpose of analgesia
ActionBinds to opiate receptors in CNS altering perception of pain, producing CNS depression
Therapeutic ClassOpioid Analgesic
Pharmacologic ClassOpioid agonists
Nursing Considerations• Use caution with increased ICP, head trauma, adrenal insufficiency • Avoid use with MAOIs • May cause apnea, laryngospasm, decreased respirations, bradycardia, hypotension • Do not consume grapefruit while taking this medication • Monitor hemodynamics during administration • Assess patient pain scale frequently
Famotidine
Trade NamePepcid
IndicationShort term treatment of active ulcer, GERD, treatment of heartburn, indigestion, management of Zollinger Ellison syndrome, prevention of GI bleeding in critically ill patients, management of symptoms associated with overuse of NSAIDs
ActionBlocks action of histamine located in gastric parietal cells, inhibits gastric acid secretion
Therapeutic ClassAntiulcer agent
Pharmacologic ClassHistamine H2 antagonist
Nursing Considerations• May cause arrhythmias, agranulocytosis, aplastic anemias • Assess for abdominal pain and occult blood • Monitor CBC • Instruct pt to increase fluid and fiber intake to prevent constipation
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Let’s face it. Pharmacology is hard. It is one of the toughest subjects in a nursing program. So if it is on your course list this coming semester, you’re probably feeling anxious and overwhelmed already.
You’re not alone. Many students, including me, have been where you are, and some even felt like they didn’t belong to nursing school anymore.
One of the most common questions we get is; “How to study for pharmacology in nursing school”?
I totally understand this. After all, being subjected to an endless list of medications and their classifications can be stressful.
Despite being difficult, pharmacology is an extremely necessary class. This is why you need a plan to handle it successfully and pass with good grades.
If you need to boost your pharmacology grades, pay keen attention to this information as I shall discuss my top tried and tested tips on how to study for pharmacology nursing.
Escitalopram
Trade NameLexapro
IndicationMajor depressive disorder, anxiety disorder, PCD, PTSD, social phobia
ActionIncreases the extracellular levels of serotonin in the synaptic cleft by selectively inhibiting its reuptake
Therapeutic ClassAntidepressant
Pharmacologic ClassSSRI
Nursing Considerations• Contraindicated with MAOI • May cause suicidal thoughts, insomnia, drowsiness, diarrhea, nausea, serotonin syndrome • May cause QT prolongation with certain medications • Assess for sexual dysfunction • May take 4-6 weeks for full affect to take place • Monitor for serotonin syndrome (mental changes, NV, tachycardia, hyperthermia)
Erythromycin
Trade NameE-Mycin
IndicationUseful in place of penicillin when patient cannot take penicillin, upper and lower respiratory tract infections, otitis media, skin infections, pertussis, syphilis, rheumatic fever
ActionBacteriostatic: suppresses bacterial protein synthesis
Therapeutic ClassAnti-infective
Pharmacologic ClassMacrolide
Nursing Considerations• Causes QT prolongation, ventricular arrhythmias • Diarrhea • Asses infection • Monitor liver function tests • Instruct patient to finish medication dosage even if they are feeling better • Medication should not be shared
Epoetin
Trade NameEpogen
IndicationAnemia
ActionStimulates erythropoiesis (production of RBCs)
Therapeutic ClassAntianemic
Pharmacologic ClassHormones
Nursing ConsiderationsAssess dialysis shunts
Contraindicated in albumin hypersensitivity
May cause
Seizures
CHF
MI
CVA
Hypertension
Do not shake vial
Initiate seizure precautions
Monitor
Bleeding times
Signs of anemia
Epinephrine
Trade NameAdrenalin, EpiPen
IndicationAsthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct
ActionAffects both beta1 and beta2 also has alpha agonist properties resulting in bron- chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.
Therapeutic ClassAntiasthmatic, bronchodilator, vasopressor
Pharmacologic ClassAdrenergic agonist
Nursing Considerations• Side effects include: angina, tachycardia, hypertension, restlessness, nervousness, hyperglycemia • Use with MAOI may lead to hypertensive crisis • Patients should not use stimulants (caffeine, guarana, etc) • Excessive use may cause bronchospasm • Assess lung sounds, pulse, BP, and other hemodynamic parameters • Monitor for chest pain • Instruct patient to use as directed • Patient should insure adequate fluid intake to liquefy secretions • Mouth should be rinsed after inhalation • Beta blockers may negate effects • May increase blood glucose levels
Lovenox
IndicationPrevention of VTE, DVT, and PE
ActionPrevents thrombus formation by potentiating the inhibitory effect of antithrom- bin on factor Xa and thrombin. Enoxaparin is a low molecular weight heparin.
Therapeutic ClassAnticoagulant
Pharmacologic ClassAntithrombotic
Nursing Considerations• Contraindicated in pork hypersensitivity • Monitor for signs of bleeding • Administer in subcutaneous tissue • DO NOT eject air bubble prior to injection • DO NOT aspirate or massage site
Enalapril
Trade NameVasotec
Indicationhypertension, management of CHF
ActionBlock conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone leading to vasodilation
Therapeutic ClassAntihypertensives
Pharmacologic ClassACE Inhibitor
Nursing Considerations• May cause hypersensitivity (allergic) reactions and angioedema (swelling of face, lips, tongue, throat)
• Can cause neutropenia – check WBCs regularly
• Use cautiously with potassium supplements and potassium sparing diuretics. • Use cautiously with diuretic therapy • Administer 1 hour before meals • Monitor blood pressure often • Monitor weight and fluid status • Monitor renal profile • Monitor CBC frequently • Dry cough
dopamine
Trade NameInotropin
What is the indication for Dopamine?used to improve blood pressure, cardiac output, and urine output
ActionSmaller doses result in renal vasodilation Doses 2-10mcg/kg/min result in cardiac stimulation by acting on beta1 receptors Doses >10mcg/kg/min stimulate alpha receptors leading to vasoconstriction (↑SVR)
What is the therapeutic class for Dopamine?inotropic, vasopressor
Pharmacologic Classadrenergic
Nursing Considerations for Dopamine (Inotropin)• Monitor hemodynamics closely: BP, HR, EKG, CVP, and PAOP if available • Obtain parameters for hemodynamic values • Titrate to obtain appropriate BP (more potent vasoconstrictors may be required) • Irritation may occur at IV site • Beta blockers may counteract therapeutic effects
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