Wall Street extended its losing streak, with the S&P 500 falling for a fourth straight day as investors braced for Nvidia’s high-stakes AI results. In company news, Microsoft and Nvidia announced plans to invest up to $15 billion in Anthropic, while Home Depot slipped after cutting its forecast on weaker demand. In the commodities market, oil prices steadied as traders weighed the impact of Russian sanctions. Back home, Aussie shares are expected to hover near five-month lows on Wednesday ahead of wages data, while CSL plans to invest $1.5 billion in US drug manufacturing.

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