Danielle M. Hess, PharmD (@dhess_09) describes the pathophysiology of opioid-induced constipation (OIC), evaluates literature depicting the safety and efficacy of peripherally-acting mu-opioid receptor antagonists (PAMORAs) for the treatment of OIC and applies the clinical pearls of PAMORAs to patient care.

For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!

You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.