National Institute for Health and Care Research

By NIHRScience

National Institute for Health and Care Research episodes

November 04, 2020 Better data equals better research equals better health care
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Catey Bunce talks to Professor Allan Gaw about the challenges and opportunities presented by #ComplexInnovativeDesign trials from a statistician's perspective.

As these trials typically answer multiple research questions, Catey explains why statistician needs to think critically about how to navigate the study so that it answers the questions without increasing the chance of a falsely significant result or even a falsely non significant result.

To find out more about how the NIHR supports complex and innovative design trials, visit the NIHR website: www.nihr.ac.uk/innovative-trials

This podcast is part of our pre-pandemic series of podcasts on Complex and Innovative Design (CID) trials. You can listen to all our full collection of #ComplexInnovativeDesign trial podcasts on our website.

11 min
August 13, 2020 Kelly Fricker: working as GP practice research nurse
Kelly Fricker is the lead research nurse at The Boathouse Surgery in Pangbourne, Reading. Here she speaks about what her role involves, studies into conditions such as arthritis and chronic obstructive pulmonary disease (COPD) and how her team are able to carry out research in their GP practice with the support of the National Institute for Health Research (NIHR).
6 min
August 04, 2020 How can Complex Innovative Design (CIDs) trials speed up the drug development pathway for immuno-oncology drugs?
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Sarah Blagden talks to Professor Allan Gaw about why she co-led a paper outlining 10 consensus statements offering guidance to the clinical research community on the design and conduct of Complex Innovative Design (CID) trials.

She explains how these types of trials can speed up the drug development pathway and help to clear the backlog of of immuno-oncology drugs that are waiting to be tested, enabling cutting edge treatments can be offered to patients sooner. Sarah also describes why she thinks the UK is ideally positioned to conduct CID studies.

To find out more about how the NIHR supports complex and innovative design trials, visit the NIHR website: www.nihr.ac.uk/innovative-trials

This podcast is part of our pre-pandemic series of podcasts on Complex and Innovative Design (CID) trials. You can listen to all our full collection of #ComplexInnovativeDesign trial podcasts on our website.
10 min
July 06, 2020 Emma Lowe — Discusses the definition of complex and innovative trials
Emma Lowe Dept. of Health and Social Care and CID Trials as she discusses the definition of complex innovative trials and on the role of the Dept. of Health and Social Care.
16 min
June 30, 2020 An introduction to complex and innovative clinical trials: Emma Lowe, Department of Health and Social Care
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Emma Lowe talks to Professor Allan Gaw about the design and delivery of complex and innovative design clinical trials.

In this episode they discuss what the term 'complex innovative design' (or CID) means in relation to clinical research. Emma explains that it focuses on 'how the research is done' as opposed to 'why it is being done'. She also highlights some of the benefits of delivering research in new and innovative ways, compared to the traditional randomised controlled trial (RCT).

The Life Sciences Sector Deal published on 5 December 2018 sets out the Government’s commitment to consolidate the UK as a world-leader in delivering complex and innovative trials. In relation to this, Emma describes some of the activities undertaken by the National Institute for Health Research (NIHR) to:
1) showcase UK expertise in designing and delivering complex and innovative design trials and;
2) to promote understanding of complex and innovative design trials across the UK clinical research workforce.

To find out more about how the NIHR supports complex and innovative design trials, visit the NIHR website: www.nihr.ac.uk/innovative-trials

This podcast is part of our pre-pandemic series of podcasts on Complex and Innovative Design (CID) trials. You can listen to all our full collection of #ComplexInnovativeDesign trial podcasts on our website.
8 min
February 20, 2020 Prof. Julie Lovegrove and Nutritional Research
Prof. Julie Lovegrove and Nutritional Research by NIHR
17 min
January 16, 2020 Prof. Martin Rossor and Dementia Research
Martin’s clinical research interests are in the degenerative dementias, particularly familial disease, and more recently in general cognitive impairment in systemic disease and multimorbidity. He established the Queen Square Dementia Research Centre and has served as the editor of the Journal of Neurology, Neurosurgery and Psychiatry, President of the Association of British Neurologists, Director of the NIHR Clinical Research Network for Dementia and Neurodegenerative diseases (DeNDRoN), and Director of the NIHR Queen Square Dementia Biomedical Research Unit. As part of the activities of DeNDRoN he established Join Dementia Research (JDR), a national system for linking patients and public to research studies.
He has served on numerous advisory boards and is currently an associate member of the World Dementia Council, member of the 2020 Dementia Programme Board, and Chairman of the Senate for the German Centre for Neurodegenerative Diseases (DZNE).
13 min
January 10, 2020 Katherine Cowan
Katherine Cowan by NIHR
17 min
December 19, 2019 Prof. Irene Higginson and Palliative Care Research
Prof. Irene Higginson and Palliative Care Research
16 min
November 06, 2019 Peter Bower Multimorbidity
Peter Bower Multimorbidity by NIHR
15 min

About National Institute for Health and Care Research

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The National Institute for Health and Care Research (NIHR): funding, enabling and delivering world-class health and care research that transforms people's lives. Visit our website: www.nihr.ac.uk