In this episode of Neonatology Now, host Mario Rüdiger speaks with Prof Eric Peebles about the evolving understanding and management of neonatal encephalopathy. They trace the history of treating hypoxic‑ischemic encephalopathy (HIE) and discuss how hypothermic therapy became an evidence-based standard. The conversation highlights the urgent need for global harmonization of neonatal data, as shown by striking inconsistencies across international registries.Prof Peebles explains how the Newborn Brain Society used a modified Delphi process with experts from 81 countries—including parent advocates—to define Core Data Elements (CDEs) that support consistent research and equitable participation worldwide. The episode also explores how digital tools and automated data extraction will shape the future of neonatal research and improve long-term, family-centered outcomes.

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