Hosts Michael Calhoun and Travis Sheridan sit down with Andrew Smith, Head of Innovation and Entrepreneurialism for the St. Louis Regional Chamber, to discuss the potential of St. Louis gaining the highly anticipated Hyperloop One.

Host Michael Calhoun sits down with Ken Niemann, President at Paramount Mortgage Company, to discuss the Paramount bank branch in North St. Louis County, and the innovations they are taking to lead the industry.

Arch Grants executive director Emily Lohse-Busch says let's build the next Amazon in St. Louis. We'll hear about the Purina Pet Care Innovation Prize and one of their start-ups, Animal Biome. Donn Rubin of BioSTL calls from Tel Aviv talks about their trip to Israel to talk digital health.

Catherine Neville, publisher of Feast Magazine, fills in for Travis this week. Michael and Cat talk about the now-released St. Louis sales pitch for Amazon and get details from Sheila Sweeney, of the St. Louis Economic Development Partnership. Also, an update on studies of a north-south Metro-Link expansion. Cat tells us about her upcoming 'Tastemakers' national television show.

Brett Kline will introduce us to Medici Marketplace, a co-working space for creative professionals. And then we'll talk via Skype with some graduates of two LaunchCode class, including CoderGirl, and get the latest on their programs.

Hyperloop promises to be a fast route of transportation and we'll get an update on the St. Louis-to-Kansas City route from St. Louis Regional Chamber VP Andrew Smith. North county's Paramount Bank aims to become the next Simple. Business travelers get a new club at Lambert Airport.

St. Louis Post-Dispatch business columnist David Nicklaus joins Michael and Travis to talk about the biggest business and innovation stories of the year. Also, Doug Auer of Third Degree Glass Factory gives us a tour of the new Maker Studio. 

Last year, St. Louis video game firm Pixel Press partnered with Mattel to more widely manufacture and distribute its game called Bloxels. This holiday season brings a deal with Disney. Pixel Press' Robin Rath stops by to explain.  Dennis Lower of the Cortex Innovation Community gets into all the district's expansion news. And Tim Schoen talks about Beer Hub opening a tap room on Oakland Avenue.

The long-delayed Loop Trolley project got a boost from St. Louis design, construction and real estate firm Clayco.  Founder and CEO Bob Clark says the company is donating cash and expertise to get the project back on track. Michael also talks with Clark about Clayco's work on Centene and Pfizer's expanded campuses and on St. Louis' bid for Amazon HQ2.

Brazen is an organization that seeks to empower women business owners. Its original name was 'Prosper Women Entrepreneurs.' Travis talks with Jennifer Ehlen of Brazen Global and Mindy Mazur of Brazen St. Louis about their programs and the current climate for women-owned businesses.