In the November 2022 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss kidney stones as well as mesenteric ischemia. As always, you’ll hear about the hot topics covered in CDEM’s regular features, including monkeypox in Clinical Pediatrics, an atypical presentation of gout in Critical Cases in Orthopedics and Trauma, management of small, bleeding tongue lacerations in The Critical Procedure, a comparison of ibuprofen regimens for acute pain in The Literature Review, and an adolescent with knee pain in The Critical Image.