JACI: In Practice Editor Michael Schatz describes the November issue, which is the American Academy of Allergy Asthma and Immunology Presidential theme issue on the subject of “Use of Artificial Intelligence in Allergy/Immunology.” The theme review articles in this issue comprehensively cover the use of artificial intelligence for diagnosis, management, patient monitoring, and patient education for asthma and allergic conditions. Dr. Schatz then presents the Highlights of the Original Articles in the issue, which are on the topics of artificial intelligence, asthma, drug allergy, eosinophilic disorders, food allergy, hereditary angioedema, and immunodeficiency.