Neuroscientist Matthew Alper presents his controversial thesis that religious experience originates in specific brain structures rather than divine contact. Author of "The God Part of the Brain," Alper argues that humans evolved neural circuitry dedicated to generating spiritual experiences as an evolutionary adaptation to cope with awareness of death. He explains how brain imaging studies of praying nuns and meditating monks reveal consistent patterns of neural activity in regions associated with religious experience. Alper suggests that all religious traditions access the same neurological pathways, explaining why mystical experiences share common elements across cultures despite different theological frameworks. He addresses the philosophical implications of his research, arguing that understanding the biological basis of religious experience doesn't necessarily negate spiritual reality but provides insight into how humans process the divine. The conversation explores whether religious experience represents genuine contact with transcendent reality or simply neurological phenomena shaped by evolution. Alper discusses the adaptive value of religious belief in promoting survival and social cohesion while acknowledging the profound meaning these experiences provide to believers. This challenging interview questions fundamental assumptions about consciousness, spirituality, and the nature of religious experience, offering a scientific perspective on humanity's deepest spiritual questions.