JACI: In Practice Editor Robert Zeiger describes the October issue, the theme of which is “Newer Diagnostic Methods in Allergy”. Theme topics covered include assessing indoor allergen exposures; laboratory tests in the diagnosis of food, venom, and drug allergies; epitope-based IgE assays and their role in the diagnosis of food allergies; chip-based assays in the diagnosis of allergic diseases; the basophil activation test; the normal range of baseline tryptase; and specific IgE cut-off levels. Dr. Zeiger then presents the Highlights of the Original Articles in the issue, which are on the topics of Anaphylaxis, Asthma, Dermatitis, Drug Allergy, Food Allergy, Rhinitis and Sinusitis, and Urticaria and Angioedema.