Maureen Callahan delivers a massive takedown of a long list of repeat offenders, kicking off with Mel Robbins' inability to defend her "Let Them" nonsense during an interview on "Real Time" with Bill Maher. Then she unleashes on Oprah's recent roundtable on family estrangement, showcasing individuals who have gone the way of "not contact " with their families and her decision to post the discussion online right before the long Thanksgiving weekend. After that, Maureen has a full celebrity lightning round on Harry's social media post with Stephen Colbert acting like a TikTok tween, Gayle King exposing her uncertainty about CBS, Jennifer Aniston's inability to hold a door for her beau, and Michelle Obama's embarrassing explanation for being "cool."Later, Maureen goes off on Amy Schumer's body image hypocrisy and her questionable reason for her massive weight loss.

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