In this interview, Dr. George du Toit and Dr. Amitha Kalaichandran discuss how to safely reduce an infant’s risk of peanut allergy with early introduction of peanut protein. They talk about the evidence behind why this works to reduce risk and they explain the recommended timing, frequency, and amount of peanut that should be given to infants.Dr. George du Toit is a pediatric allergy physician at Evelina London Children's Hospital in London, UK. He is also one of the lead researchers for the LEAP (Learning Early About Peanut Allergy) study. Dr. Amitha Kalaichandran is a pediatrics resident physician and epidemiologist based in Ottawa.They co-authored a practice article published in the Canadian Medical Association Journal. Full article: www.cmaj.ca/lookup/doi/10.1503/cmaj.181613Additional resources:Canadian Paediatric Society Practice Point — Timing of introduction of allergenic solids for infants at high riskhttps://www.cps.ca/en/documents/position/allergenic-solidsNEJM LEAP Studyhttps://www.nejm.org/doi/full/10.1056/NEJMoa1414850NEJM EAT Studyhttps://www.nejm.org/doi/full/10.1056/NEJMoa1514210NEJM LEAP-ON Studyhttps://www.nejm.org/doi/full/10.1056/NEJMoa1514209Review — Early introduction of foods to prevent food allergyhttps://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0286-1 Canadian Society of Allergy and Clinical Immunologyhttps://csaci.ca Food Allergy Canada patient support grouphttps://foodallergycanada.ca/our-impact-advocacy-and-services/programs-and-services/support-groups/----------------------------------------------------------------------This podcast episode is brought to you by Audi Canada.The Canadian Medical Association has partnered with Audi Canada to offer CMA members a preferred incentive on select vehicle models. Purchase any new qualifying Audi model and receive an additional cash incentive based on the purchase type. Details of the incentive program can be found at www.audiprofessional.ca.-----------------------------------Subscribe to CMAJ Podcasts on Apple Podcasts, iTunes, Google Play, Stitcher, Overcast, Instacast, or your favourite aggregator. You can also follow us directly on our SoundCloud page or you can visit www.cmaj.ca/page/multimedia/podcasts.

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