One of America's most successful serial killers was Martha Grinder, an Allegheny County woman who rose to notoriety in the years following the Civil War as "The Poisoner of Gray's Alley". What made Martha Grinder so successful in playing her deadly game, aside from the fact that she killed indiscriminately for years before getting caught, was that she appeared beyond reproach-- for Martha was adored by her neighbors and was regarded as one of the kindest-hearted women in the Pittsburgh area.