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Callie Isley is 36, lives in Texas, and spent five years trying to become a mother — multiple fertility evaluations, IUIs, and a looming $25,000 IVF bill — before her story took an unexpected turn. In this deeply personal episode, Dr. Kylie Burton and Jessica Brickie sit down with Callie to talk through the emotional weight of infertility, the lifestyle changes that came before her pregnancy, and the surprise that changed everything.
Callie walks through her and her husband's fertility journey: a low egg reserve diagnosis, her husband's low sperm motility, two failed rounds of IUI, and the sticker shock of IVF pricing with no insurance coverage. She's candid about the depression that set in as the years passed and friends around her started families of their own. A visit to her mother's holistic doctor — prompted by her mom, not her own initiative — led to bloodwork, a hard look at her lifestyle (including what she calls her "DoorDash diet"), and a recommendation to try microdosed tirzepatide. Six months and about 50 pounds later, she'd planned to come off the medication to prepare for IVF — and discovered she was pregnant instead.
The conversation doesn't stop at the pregnancy news. Callie, Kylie, and Jessica dig into the emotional and relational toll infertility takes, the stigma around GLP-1 use that kept Callie from trying it sooner, and the broader idea that these peptides may be addressing an underlying metabolic picture — not just facilitating weight loss. The hosts are careful throughout to frame this as one woman's story and not a guarantee or a fertility treatment protocol.
What You'll Learn
Segment Breakdown
Guest
Callie Isley lives in Texas with her husband. After a five-year fertility journey, she is now expecting and has chosen to share her story to support others navigating infertility.
Find Callie: Instagram, Facebook, and TikTok — @Callieeisele (spelled C-A-L-L-I-E E-I-S-E-L-E)
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
The peptide world is full of hype, half-truths, and confusing acronyms, so we’re slowing down and getting specific about two names that keep showing up: BPC-157 and TB-500.
Ready to understand BPC-157 (Body Protection Compound) in plain English and why its headline is tissue repair? Next up is the peptide it's often combined with: TB-500, a thymosin beta 4 fragment. It works with actin inside your cells, helping the “right” cells migrate to the “right” place when your body is trying to recover.
Our favorite way to remember this Wolverine Stack and the first peptide Dr. Kylie started is: TB-500 directs traffic, BPC-157 does the road work.
From there, we bring it to real life with stories from past guests and our own experiences using this peptide combination:
Not ready for injections? Dr. Kylie wasn't either. Capsules are available.
If you’re curious about the Wolverine Stack (BPC-157 and TB-500)as it helps with recovery, are peptides for tendon and ligament support, and peptides for gut health, tune in. Then share it with your audience so they can benefit from this peptide stack too.
BPC-157 and TB-500 are the peptides that'll have you saying "is it possible to feel this good at this age?"
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
Why do GLP-1 peptides keep showing up in places like heart health, kidney function, inflammation, sleep apnea, joint pain, cravings, and even long-range conversations about aging? Yet, most people believe they only have a positive impact on weight loss.
If you believe GLP-1s are only good for weight loss, think again.
We make the science simple without dumbing it down:
We also slow way down for the most sensitive topic: cancer. We share what large observational datasets are suggesting, why that is not the same as proof, and why this is never a reason to gamble with gray market peptides or start anything without your oncology or medical team involved.
Studies have also shown improvements in two areas nobody saw coming: improved obstructive sleep apnea results in trials, and shifts in the brain’s reward loop that may affect alcohol, nicotine, gambling, opioids, and disordered eating.
If this conversation helps you think more clearly about GLP-1 medications, peptides, and evidence-based wellness, subscribe, share this with a friend who only hears the commercials and fear tactics. Help everyone you know understand GLP's go far beyond weight loss and the benefits just keep stacking up.
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
Why are we talking about Hormone Replacement Therapy on a Peptide Podcast? Well, peptides and hormones go great together and now, you have access to BOTH with our telemedicine company.
The topic is needed too. 80% of women show up to a menopause-related doctor visit and walk out with no treatment. Not “no hormones” no treatment at all.
That stat frames a bigger problem we see every day: when you say “I don’t feel like myself,” the system often has no place to put you unless your labs or imaging scream in black and white.
We sit down with the Nurse Practitioner Jess works with, Crystal Harter, an HRT expert who built her practice around the opposite model: more time, more listening, and real follow-up. We talk through:
What about adding hormones to your blood work panel? Crystal days "don't bother." It's misleading during perimenopause because fluctuations make “in range” results meaningless for many patients.
We also get practical about hormone replacement therapy: why it’s rarely one-and-done, how dosing and delivery routes matter (oral vs transdermal), and why “HRT didn’t work for me” often just means the plan wasn’t managed long enough or tailored well enough. We cover prevention benefits like bone health and osteoporosis prevention, plus the bigger picture of cardiovascular disease, insulin resistance, and brain health.
Men, we can't leave you out of the picture either. Men can be affected by low testosterone, low libido, and more. When possible we highly recommend when you're in a partnership, both couples take a look at their hormones. We don't want either one of them to be out of sync.
If you’ve been told you’re too young, your labs look fine, or your symptoms are “just stress,” press play and take notes. Subscribe, share with a friend who needs this conversation, and leave a review so more people can find real menopause and perimenopause help using hormones and peptides.
To connect with Crystal, visit her website at https://www.hudsonvalleybeautylab.com/estheticians-in-newburgh/1465-2/ or her Instagram at https://www.instagram.com/crystal_harter_np/
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
What if you didn't need a certification, a finished weight loss journey, or even a full understanding of peptides to build a thriving business around them? Tanya from Sydney, Montana is proof that all you really need is a source, a system, and the willingness to show up.
In this bonus business episode, Dr. Kylie Burton and Jessica Briecke sit down with Tanya Candy, RN, whose peptide business journey started with a cold DM she almost dismissed — and a handmade sign in her front yard that stopped traffic in a town with one stoplight.
In this episode you'll hear:
You don't need to be an expert. You don't need a finished story. You just need to start.
Find Tanya: Website: awakenwellnesslc.com Facebook, Instagram, TikTok & YouTube: Tanya Candy, RN Located in Sydney, Montana
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
Ready to make money when you leave the office? This isn't just a dream for Jessica anymore. It's reality.
Peptides get talked about like a trend, but what we really want is lasting change: more energy, more options, and a life that isn’t chained to the clock. We open with a simple idea that hits hard, we don’t work only to pay bills. We work to build dreams, and today Jess shares what it feels like when a decades-long goal finally becomes real.
Jess gets emotional walking us through closing on a second home in Florida, just minutes from the beach! Her dream has become a reality. All from saying yes to an opportunity that she could get behind and going after it.
35 years as a massage therapist, she knows the reality of a physically demanding, time-for-money career, and why longevity matters when your income depends on you being in the office.
Dive inside as we learn what brought her the income to step away from the office and at the same time, what pays for the second home in her dream location.
But this story goes deeper than real estate. This decision also supports their son’s transfer to flight school, giving him stable housing and helping the family avoid throwing money away on rent while he trains for a career that’s long and expensive.
Leave it to Dr Kylie to leave you with a mindset reminder: work smart AND hard.
Share this with a friend and if you haven't yet, subscribe for more. We drop episodes at random. Pep Talk, share this with a friend chasing a big goal, and leave a review telling us: what dream are you ready to fund next?
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
The internet loves a scary headline, and “peptides placed in category two” might be the most misunderstood one yet. We’re Dr. Kylie Burton and Jessica Briecke, and we’re slowing the noise down to explain what’s actually happening with the FDA’s July 23–24 hearing and why it directly affects patient access to compounded peptides.
It started back in 2023 when compounding pharmacies pushed back against government regulation. What happened then and what's happening now revolves around the FDA's category 1 and category 2 classifications. These classifications affect our access to them.
What exactly do these classifications mean though? And what's the difference between the DEA and the FDA?
Inside this episode, we also tackle:
Let's face the reality: when regulated access disappears, people will get pushed into the gray market with questionable sourcing and risky kitchen mixes. It's already bad enough. We don't want it to become worse.
If you care about peptide therapy, compounding pharmacy policy, and safe wellness options, hit play, share this with someone who’s seeing the misinformation, and leave a review so more people can find clear answers.
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
A teratoma on her ovary. Then Hashimoto's. Then breast cancer. When it rains, it pours — and for Jen Gifford Wersland, it absolutely did.
In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Jen, a breast cancer survivor whose story is equal parts harrowing and hopeful. From being dismissed in the ER with an IBS diagnosis (while carrying a peach-sized ovarian tumor) to navigating 12 rounds of chemo, a mastectomy, sudden menopause, and a reactivated Epstein-Barr virus — Jen's body had been through war. And the inflammation to prove it.
Then her oncologist brought up microdosing tirzepatide. And Jen almost walked out.
In this episode you'll hear:
If you've been told peptides aren't safe after cancer, this episode is a must-listen. And if you've been quietly suffering and putting everyone else first — Jen has something to say to you too.
Find Jen: Facebook: Jennifer Gifford Warsland Instagram & TikTok: @ThrivingAfterBreastCancer
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
What if the migraines you've managed your entire life weren't just about triggers — but about what your body was never making in the first place?
In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Amy Cassles, a health-conscious, fitness-minded woman who spent 35 years doing everything right — and still couldn't outrun her migraines. From blood pressure meds and anti-seizure drugs in her teens and 20s, to a candida cleanse, sinus surgery, breast implant removal, and even a partial hysterectomy — Amy tried it all. And still, one stressful moment could send her to bed, vomiting, unable to open her eyes.
Then she discovered something she'd been skeptical of for years.
In this episode you'll hear:
Bonus: we had to share Amy's mom's arthritis turnaround too.
If you know of someone who suffers with migraines and/or arthritis, please forward this episode to them.
If you or someone you love suffers from chronic migraines — or has written off GLP peptides because of the horror stories — this episode is for you.
Find Amy: Instagram: @creationliving | @acastles Facebook: Amy M Cassles
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
Everyone wants glowing skin. But what if the serum, the cream, and the collagen powder aren't the problem — and neither is your skincare routine?
In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Jen Gifford Wersland and Tanya Candy, RN, two women from Montana who stumbled onto a peptide-powered skincare approach that's turning heads — literally. People started stopping them to ask what they were doing differently. The answer surprised everyone.
In this episode you'll hear:
If you've been doing all the right things for your skin and still not seeing results, this episode will change how you think about skincare from the inside out.
Find Jen: Facebook: Jennifer Gifford Wersland Instagram: @ThrivingAfterBreastCancer
Find Tanya: Facebook Business Page & Website: awakenwellnesslc.com Facebook Personal: Tanya Candy, RN
Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com
Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop.
Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylieburton.com/peptidesaffiliate. You can also get started through Jessica's platform at B2BwithJess.com.
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
You have the science. You have the tools. Now it's time to take the next step.
This is PepTalk: Peptides Unpacked—science made simple, re...
From the publisher's feed
Peptides are revolutionizing modern medicine—but the science can feel overwhelming. That's where we come in.
Join Dr. Kylie Burton, Functional Medicine Practitioner, and Jessica…
Inside this limited series podcast, we explore:
This podcast is designed for the curious health optimizer, the wellness practitioner ready to level up, and anyone who believes healing should be both cutting-edge and grounded in fundamentals.
Ready to explore advanced peptide therapy? Get started at drkylieburton.com
Legal Disclaimer: This podcast is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new health protocol. Dr. Kylie Burton and Jessica Briecke are affiliates and may receive compensation for referrals. Individual results may vary.
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