Physicianary

This special edition episode features the latest installment of Healio Community's book club. Physician author Eric Topol, MD, discusses his book, Super Agers: An Evidence-Based Approach to Longevity, a guide to the science of living a long life free of debilitating diseases with Leonard H. Calabrese, DO, chief medical editor of Healio Rheumatology. • Intro by Hansa Bhargava, MD 0:52 • A warm welcome by Leonard H. Calabrese, DO 1:38 • Introducing Eric Topol, MD 1:57 • "Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again" but did you think it would happen this fast? 2:49 • Let's get into "Super Agers" 4:34 • What's killing most people? 7:28 • An evidence-based treatise on healthy aging 10:44 • The role of immune health in longevity 14:15 • What's next on the horizon? 16:57 • A candle in the dark 21:56 • Minimizing the risk of getting old while you age 24:15 • The influence of health behaviors on immunologic wellness 27:08 • The hot issues: GLP-1's 28:31 • A new world for immunology 33:33 • Thank you, Dr. Topol 35:09 • Thanks for listening 35:29 We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected].

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Disclosures: No products or companies that would require financial disclosure are mentioned in this episode.

In a special edition episode recorded at this year's Fierce Pharma Conference, Physicianary host, Hansa Bhargava, MD, joins Cynthia Matossian, MD, FACS, Todd Armstrong, and Mark Bard for a panel discussion about clinical and industry opinions surrounding AI in health care. • Intro 1:45 • Healio asked about 550 physicians, "What is your opinion of AI"? 2:36 • Todd, AI is part of the clinical workflow. […] What does it mean for advertisers, brands and publishers? What are the concerns and misconceptions? 3:26 • What is the biggest trend you've seen surrounding AI in clinical workflow? 6:45 • Dr. Matossian, what is the value of AI to clinicians? How is it changing the way we practice medicine? 9:41 • What do you think is making some physicians hold back when it comes to relying on AI? 12:35 • Is it ethical and safe as a brand to use AI-generated tools for sales follow-up calls? 13:46 • Hansa, how do you convey the value of AI tools, especially from vetted sources? 15:41 • Discussion on the value of transparency. 18:49 • Final thoughts? 20:05 • Thanks 23:40 Todd Armstrong is a senior vice president and group media lead at CMI Media Group.

Mark Bard is a new media, marketing, and technology entrepreneur.

Cynthia Matossian, MD, FACS, is the founder and medical director of Matossian Eye Associates, an integrated ophthalmology and optometry private practice.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected].

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava reports no relevant financial disclosures. Armstrong reports he is the Group senior vice president of engagement strategy at CMI Media Group. Bard reports he is co-founder of The DHC Group. Matossian reports being CEO of GPOphtho.

In this episode, guests Dylan Attard, MD, Keith Grimes, MD, and Muhammad Mamdani, MD, PhD, discuss global innovation, doctorpreneurship and the ethics of AI in health care. • Intro 1:16 • Dylan Attard, MD 2:08 • Keith Grimes, MD 2:47 • Muhammad Mamdani, MD, PhD 3:20 • Muhammad, what is a general definition of AI? Can you further elaborate on what predictive analytics versus generative AI? 4:26 • Would you agree that AI provides an exponential way of processing information? 7:26 • Keith, do we need to be aware of guardrails? In general, what are those guardrails? 7:55 • Dylan, when you meet a doctorpreneur, do you feel like they have a good understanding of AI and innovation? If so, how did they get there? 10:23 • Do you find that when you've made career pivots, it feels like starting from scratch? 12:49 • Is the thought that doctors who want to be entrepreneurs "can't check their ego at the door" true? If so, is it a challenge? 14:54 • Muhammad, can you tell us about Unity Health Toronto and how it has been driven by use cases? 18:12 • Keith, what are some of the barriers preventing countries from being able to use another country's AI tools? 23:18 • Dylan, do you agree? Are there challenges to cross borderlines for innovation? 27:49 • Group discussion on improving collaboration in innovation and access to AI. 29:28 • Keith, do you think that the UK and Europe's outlook on AI regulation versus the US will become an arms race? 31:57 • Muhammad, being from Canada, what are your thoughts on global regulations? 33:47 • Dylan, have you seen any switching in usability studies from one location to another due to greater bandwidth in certain countries? 36:31 • Discussion on questioning the safety of technology. 39:09 • For doctors and clinicians listening, what is the best way to learn and get involved? 40:06 • Any advice for doctors thinking about career pivots? 41:57 • What is your favorite science-fiction movie? 43:33 • How can people contact each of you? 44:25 • Thanks 44:48 Dylan Attard, MD, is a Maltese physician and entrepreneur. He is the co-founder and CEO of MedTech World, a global platform dedicated to advancing healthcare innovation.

Keith Grimes, MD, is founder and CEO of Curistica, a health tech innovation consultancy dedicated to helping builders and buyers of Clinical AI innovate faster, safer, and smarter.

Muhammad Mamdani, MD, PhD, vice president of data science and advanced analytics at Unity Health Toronto and director of the University of Toronto Temerty Faculty of Medicine Centre for Artificial Intelligence Research and Education in Medicine (T-CAIREM).

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. For more from Attard, follow him on LinkedIn. For more from Grimes, follow him on LinkedIn. For more from Mamdani, email him at [email protected].

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava reports no relevant financial disclosures. Attard reports he is co-founder and CEO of MedTech World. Grimes reports he is founder and CEO of Curistica. Mamdani reports receiving honoraria for speaking engagements and one-time advisory boards from Baxter, Lily, Takeda and Werfen, research funding from Roche and is an Advisor to Mutuo Health and Signal 1.

In this episode, guest Sachin Jain, MD, discusses methods to expand access to underserved patient populations, and how physicians should maintain their "inner voice" to combat demoralization. • Intro 1:14 • Sachin Jain, MD 1:28 • How do you do it all? 2:23 • What drove you to work with SCAN? 3:04 • What were some of the pathways to your success metrics? 6:02 • How do you feel about the passing of The One Big Beautiful Bill Act? 8:00 • How do the factors that impact vulnerable communities all play together? What does the health care landscape look like two to five years from now? 10:38 • Bhargava and Jain on the crisis affecting physicians' "joy of work". 13:13 • What can we do about the physician burnout crisis? 14:49 • Did you ever get burnt out, and if so, how did you change your pathway? 15:58 • Is it difficult to communicate with people who have not grown up how you have in a health care profession? 18:50 • How do physicians turning to business continue to carry the torch of humanity in medicine? 20:35 • How can AI change medicine? Do you think AI can help us in our inefficient delivery of medicine? 22:00 • Do you think doctors should prepare for AI? If so, how? 24:27 • Bhargava and Jain on work-life balance. 26:19 • What is your favorite movie or book? 29:21 • Thanks 30:59 Sachin H. Jain, MD, MBA, FACP, is CEO of SCAN Group and SCAN Health Plan, one of the nation's largest not-for-profit Medicare Advantage plans, which serves more than 300,000 members.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. For more from Jain, contact him on LinkedIn.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava and Jain report no relevant financial disclosures.

In this episode, guest Anthony Chang, MD, returns to discuss the medical benefits of utilizing AI technology in concert with human thinking, and governing AI in health care. • Intro 2:36 • Anthony Chang, MD 2:50 • How do you do it all? 3:40 • What drove your interest in AI? 5:12 • Bhargava and Chang on how nature and medicine can be mathematical. 7:42 • Bhargava and Chang on combining analytical thinking and gut feelings as physicians, and how AI plays a role in this combination. 13:50 • Do you feel that physicians and AI should work in silos, or should they work together? How do you ensure that this collaboration is a smooth transition? 15:12 • How can the average clinician, how do we bring them to the table and get them to use these tools so we can get the best results? 19:26 • Is scheming in AI something that concerns you? 23:22 • How can we ensure that there are more guardrails in AI governance? 26:17 • Who is responsible if AI makes an incorrect decision and the physician acts on it? 27:43 • If there is an AI tool that has been proven to help patients (i.e. in early detection), could an institution be legally liable for not using the tool? 29:05 • How can more physicians be brought to the table to design these tools and be better equipped to handle the major challenges presented by AI governance? 30:51 • Should clinicians be getting board certified to become digital translators, or are there other ways to become "bilingual"? 34:32 • What are some resources you can share with physicians who are interested in learning more about becoming fluent in AI, and tell us more about your conference, AIMed25? 36:22 • What does the world look like in five years related to AI in health, according to Anthony Chang? 40:06 • Thanks 46:38 Anthony Chang, MD, MBA, MS, is a pediatric cardiologist with a MS in data science from Stanford and a certification in AI from MIT. He is the medical director of the heart failure program at Children's Hospital of Orange County and chief intelligence and innovation officer of CHOC where he founded the CHOC Sharon Disney Lund Medical Intelligence, Information, Investigation and Innovation Institute or Mi4. Chang is a national and international leader as a speaker, author, convener and the founder of numerous successful societies including the International Society for Pediatric Innovation, AIMed, ABAIM, providing education and certification in AI, the Medical Intelligence Society and most recently created the Alliance for Centers in Artificial Intelligence in Medicine, along with PCAIM, its pediatric component, now with over 100 centers from around the globe.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. For more from Chang, contact him at (949)-547-8902. Learn more about AIMed25, happening November 10-12, 2025 in San Diego, CA.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava and Chang report no relevant financial disclosures.

In this episode, guest Aditi Joshi, MD, discusses the benefits of institutions using telemedicine to combat physician burnout, and challenges facing making this form of health care more accessible. • Intro 2:34 • Aditi Joshi, MD 2:58 • Can you talk about your experience with burnout as an emergency medicine doctor? 4:05 • Do you think that one of the interventions for burnout might be to explore other things that fulfill you? 5:58 • Tell me more about your journey into telehealth, which eventually led to writing your book, Telehealth Success: How to Thrive in the New Age of Remote Care. 8:45 • What happened to telehealth after the pandemic, and what do you make of the new challenges facing telehealth? 12:28 • What are the challenges to making telehealth programs more scalable and accessible? 16:33 • As we move forward with AI, do you see these technologies as an advantage or a disadvantage to moving the needle forward with telehealth? 19:17 • Are there any limitations to telehealth? […] Is there anything that you worry about? 22:04 • What are your thoughts on more medical students skipping residency to move into spaces like telehealth earlier in their careers? 24:50 • Tell me about where you live now and what drove your decision to make this life change? 26:45 • What are your favorite things about living abroad in Paris, France? 28:15 • If you were the queen of the world, what would you do to change things short-term and long-term in global digital health? 29:20 • How to reach Joshi. 30:53 • Thanks 31:15 Aditi U. Joshi, MD, is a global digital health consultant, bestselling author and emergency medicine physician.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. For more from Joshi, connect with her on LinkedIn.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava reports no relevant financial disclosures. Joshi reports she is the founder of Nagamed consulting.

In this episode, guest Srimanasi (Mani) Javvaji, MD, discusses the mental and physical impact social media skincare trends can have on young patients, and popular myths surrounding skincare. • Intro 2:34 • Mani Javvaji, MD 2:46 • Can you give us a little bit of background about how you got into dermatology? 3:30 • There is a huge trend in skincare in young teens and preteens […] Have you noticed this in your practice? 5:12 • How can trending skincare products or routines affect the mental health of teens? 8:37 • Do you think that parents contribute to driving these pressures from social media? 9:42 • What are the physical effects of teenagers using non-age-appropriate skincare products? 10:23 • If you're using exfoliants more than necessary, will that increase your exposure to potential allergens which could lead to conditions like contact dermatitis? 12:28 • Can overexposure to harmful ingredients also increase your risk of sun damage? 13:59 • Is there any harm in using a lot of makeup? 15:40 • For women in general, are you seeing that women in all age groups are using more makeup and skin products than before? 17:53 • Bhargava and Javvaji on common skincare myths. 19:05 • For those in their thirties, forties, fifties and sixties do you need to exfoliate every day, or is it recommended to use less frequently? 22:15 • What are your thoughts on dermabrasion and microneedling? 23:15 • What would you recommend physicians advise their patients on about skincare and overuse of products? 24:23 • How to reach Javvaji. 26:22 • Thanks 27:14 Srimanasi (Mani) Javvaji, MD, is a Columbia University-trained double board-certified dermatologist and fellowship-trained Mohs skin cancer surgeon.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. For more from Dr. Javvaji, follow @mani.jaye.md on Instagram and @ManiJayeMD on YouTube.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava and Javvaji report no relevant financial disclosures.

In this episode, guest Soma Sengupta, MD, PhD, discusses how patients and caregivers can combat burnout, and programs to support clinicians who are also caregivers. • Intro 0:25 • Soma Sengupta, MD, PhD 0:40 • Can you give us a little background about you? 0:56 • What has driven your vision for your career? 2:32 • In addition to understanding being a caregiver personally, were you also inspired by the need for cancer patient care outside of the traditional Western deliveries? 3:45 • What threads did you focus on during fellowship that became your priorities in integrative neuro-oncology? 5:12 • What would you say to physicians considering these "out-of-the-box" treatments? 6:53 • Have you found that patients are also seeking alternative treatments? 8:05 • How important is it that physicians are well-versed in alternative therapies? 9:34 • What support systems do patients' surrounding family and caregivers need? 10:45 • Would you say that the elements of physician burnout affect outcomes? 12:41 • Can you talk about your own personal journey as a caregiver? 13:33 • Have you had the opportunity to support clinicians experiencing burnout? 15:22 • Is there any advice that you have for physicians who are experiencing burnout or want to seek more information about alternative therapies? 16:36 • What is your favorite food? 18:29 • How to reach Sengupta. 20:08 • Thanks 20:26 Soma Sengupta, MD, PhD, MBA, is a British-American physician-scientist. She is a specialty board certified neuro-oncologist board certified neurologist and fellowship-trained in integrative medicine. She is a full-time faculty member in the departments of neurology and neurosurgery at the University of North Carolina at Chapel Hill, where she is a full professor, vice chair, member of the Lineberger Comprehensive Cancer Center, and chief of the division of neuro-oncology.

We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. Follow Dr. Bhargava on X @hansabhargavaMD and on Instagram @doctorhansaMD. Sengupta can be reached via email [email protected].

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava and Sengupta report no relevant financial disclosures.

In this episode, guest Meenesh Bhimani, MD, discusses the importance of clinicians bringing their experience to the implementation of AI in health care, and how clinicians can get involved with the development of these tools and models. • Intro 0:25 • Meenesh Bhimani, MD, MHA 0:38 • Can you give us a little background about you? 0:56 • What drove you to make so many pivots in your career? 1:57 • Was there anything specific that fueled your journey into administration and leadership roles? 3:33 • How can AI help health care, and how do we ensure that it's integrated properly? 5:49 • From a clinician standpoint, if you were king of the world, what would you advise hospitals to figure out what makes sense for them when it comes to AI? 7:58 • What can be done differently to avoid issues created by AI tool rollouts? 10:22 • How do we ensure technology is safe and remains safe? 12:09 • How can doctors get involved with using AI in some capacity? 14:32 • Do you have a favorite book or TV series? 16:22 • How to reach Bhimani. 17:28 • Thanks 17:40 Meenesh Bhimani, MD, MHA, is the chief medical officer and co-founder of Hippocratic AI, a safety focused large language model for the health care industry. We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. Follow Dr. Bhargava on X @hansabhargavaMD and on Instagram @doctorhansaMD. Follow Bhimani on LinkedIn.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava reports no relevant financial disclosures. Bhimani reports he is chief medical officer and co-founder of Hippocratic AI.

In this episode, guest Austin Chiang, MD, discusses the influence of social media in medicine and how AI continues to change the health care landscape. • Intro 0:25 • Austin Chiang, MD, MPH 0:33 • Tell us about your journey. 1:00 • How did you get involved with being a social media officer at your institution? 3:43 • Where do you think doctors should see themselves in the future of social media in medicine? 6:25 • What are the ways in which you see AI tech making a difference? 9:03 • Do you agree that it is helpful for doctors to be involved with product development and integration on an industry level? 12:05 • Can you give us some insight on the process of putting through new CPT codes as a company? 14:32 • Tell me more about your book, Gut: An Owner's Guide (The Body Literacy Library). What motivated you to write this book, and what do you think people will get out of it? 18:27 • If you were the "king of health care", what would you work on first? What is the most important aspect of health car that you think needs fixing? 21:23 • What's your favorite food? 25:23 • How to reach Chiang. 26:00 • Thanks 26:18 Austin Chiang, MD, MPH, is the first chief medical officer for the endoscopy business of Medtronic, the global leader in health technology. He is also currently an assistant professor of medicine at an academic teaching hospital in Philadelphia, PA, and serves as the director of the Endoscopic Weight Loss Program. We'd love to hear from you! Send your comments/questions to Dr. Bhargava at [email protected]. Follow Dr. Bhargava on X @hansabhargavaMD and on Instagram @doctorhansaMD. Follow Chiang everywhere on social media @AustinChiangMD.

Become a member of the Physicianary Fan Group and keep the conversation going! Join episode discussions, share your insights and leave your questions for Hansa and her guests. Go to community.healio.com and register today!

Disclosures: Bhargava reports no relevant financial disclosures. Chiang reports he is the chief medical officer for Medtronic Endoscopy.