The history of disease demonstrates both the accidental nature of history and the triumph of human reason that can enable us to gain some control over our fate; most of us no longer suffer the death of half our children, among other nightmares. William McNeill's book, Plagues and Peoples, was the first comprehensive history to capture this balance, and after more than 40 years it remains one of the most insightful narratives on how disease has both shaped and been shaped by civilization.

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