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Podcast Notes Playlist: Latest Episodes
Podcast Notes Playlist: Latest Episodes episodes
- #541 A Walk Through the 2026 Lipid Management GuidelinesThe Curbsiders Internal Medicine Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------
Cardiovascular disease caused by hyperlipidemia is the leading cause of death worldwide, but it doesn’t have to be! We have the tools to treat this widespread problem. Dr. Daniel Edmundowicz (Temple University) takes us through how to keep lipids where they should be, low.
Claim CME for this episode at curbsiders.vcuhealth.org!
Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME
Show Segments- Intro
- Case
- Topic
- Rapid fire questions/Picks of the Week
- Outro
Credits- Written and Produced by: Deborah Gorth MD, PhD
- Infographic and Cover Art by: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH
- Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
- Reviewer: Emi Okamoto MD
- Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
- Technical Production: PodPaste
- Guest: Daniel Edmundowicz MD, MBA, FACP, FACC
Disclosures
Dr. Edmundwicz reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures.Sponsor: Babbel
Go to Babbel.com/CURB for up to 60% off.
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0 min - Bill Ackman: The Biggest Fight of His LifeKnowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Bill Ackman is the founder and CEO of Pershing Square Capital Management, one of the most closely watched investment firms in the world.In this conversation, he breaks down how he tells the difference between real innovation from hype, what he looks for before making a billion-dollar investment, and why he sold Netflix—and later bought it back. He also shares the mistakes that reshaped his investment process and his plan to build a modern-day Berkshire Hathaway.Bill also opens up about something far more personal: his daughter Lucy’s sudden brain hemorrhage, the hours before surgery, and her ongoing recovery. He describes running his business from a hospital room and the institute he and his wife are building to help other families facing similar challenges.Enjoy!-----Chapters:(00:00) Intro(00:53) The Night His Daughter Nearly Died(08:49) His Plan to Rethink Brain Recovery(16:15) Could Her Ring Have Raised the Alarm?(17:07) How He Holds It Together(23:17) How Bubbles Pull You In(23:49) Is Venture in a Bubble?(25:23) When Easy Money Runs Out(28:05) He Hated the Idea. He Invested.(30:05) Who Actually Profits From AI?(35:53) The Rules He Carved in Stone(39:15) The Trade He Won't Make Again(42:02) Why He Consults "Dr. Claude"(46:14) Waiting for a Cheaper Market?(48:20) Netflix: Why He Changed His Mind(51:36) Howard Hughes and The Assets Nobody Wanted(53:22) What If You Owned a City?(01:00:02) Berkshire's Most Overlooked Advantage(01:04:36) From Watch Buyer to Company Owner(01:09:42) How He Judges CEOs in an Hour(01:14:19) What's Left to Achieve at 60?-----Follow Bill Ackman:X: https://x.com/BillAckman-----Newsletter: The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter------Follow Shane Parrish:X: https://x.com/shaneparrishInsta: https://www.instagram.com/farnamstreet/LinkedIn: https://www.linkedin.com/in/shane-parrish-050a2183/-----Thank you to the sponsors for this episode:+Applovin: Launch your first AppLovin campaign and grow your business: https://applovin.com/shane+HeyGen is a message-first AI video platform that helps people and AI agents turn ideas into professional video in minutes. Try for free at https://www.heygen.com/tkp+Matic: the robot vacuum that does it all—grab yourself a year of free bags here. http://maticrobots.com/shaneparrish+LMNT: My go-to zero sugar electrolytes — get a free LMNT Sample Pack here: https://DrinkLMNT.com/TKP-----+ Members get the longer, extended version of this conversation, with additional content not included in the public release.Learn more: https://fs.blog/membership/-----Note: Shane and guests may hold positions in assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. Nothing in this conversation should be considered investment advice, financial guidance, or a recommendation to buy or sell any security. Always do your own due diligence or consult with a qualified financial advisor before making investment decisions.Learn more about your ad choices. Visit megaphone.fm/adchoices0 min
- Rick Rubin: What Jay-Z Did in 30 Minutes Left Me Speechless!The Diary Of A CEO with Steven Bartlett: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Discover the spiritual and psychological creative process that legendary producer Rick Rubin uses to help the world's biggest artists transcend and achieve greatness.Rick Rubin is the co-founder of Def Jam Recordings, and the author of the philosophical bestseller The Creative Act: A Way of Being. Having collaborated with icons like Jay-Z, Johnny Cash, Adele, Tom Petty, and Kanye West, Rubin does not rely on commercial metrics or audience testing to guide his workflow. He shares practical strategies for dismantling the prisons of identity, harnessing the power of "indefensible" ideas, and cultivating a state of pure creative freedom.In this episode, he explains:■ The "Indefensible" Act: Why the greatest artistic breakthroughs defy logic and market research.■ The Vacuum Strategy: How walking away from obligations that no longer serve you creates an energetic void, allowing the universe to present massive unexpected opportunities.■ The Audience Trap: Why focusing on commercial incentives and audience expectations completely undermines the creative process.■ Deconstructing the Greats: The psychological traits that separate good musicians from generational icons.■ The Trauma of Success: Rubin opens up about his crippling depressive episode at age 33 after a corporate restructuring at Def Jam.Chapters00:00:00 Intro00:02:38 Rick Rubin’s "Indefensible" Rule00:05:24 How a Meme Became Rick Rubin's "The Way of Code"00:10:34 Why Risk Beats "More of the Same"00:16:43 How Jay-Z's 99 Problems Was Made00:20:47 Transcendental Meditation & Finding What You Love00:29:00 Is Creativity Innate?00:33:51 Stop Comparing Yourself00:35:47 The "Lazy Workaholic" & Avoiding Deadlines00:38:23 The 4 Phases of Creativity00:41:04 Should You Quit Your Job to Chase Your Dream?00:48:15 How Rick Rubin Knows an Artist Will Be Great00:54:15 Feeling Boxed In? The “Reset Button" for Your Life00:57:50 Ads00:59:47 Your Identity Is the Trap: How to Start Over01:07:39 My Depressive Episode at 33 and What It Taught Me01:17:11 How to Be More Original01:27:52 Is AI Dangerous?01:29:24 Can AI Be Creative?01:35:09 What Makes a Great Artist in the AI Era?01:40:27 Studio Miracles01:46:45 When the World Rejects Your Work01:54:24 The Ace of Spades Story: Why Jay-Z Walked Away From Cristal02:01:00 Ads02:02:24 What If Your Art Isn't Good?02:07:03 What Made Jay-Z Different: Inside His Writing Process02:17:35 What Makes Kanye Brilliant + Were Great Artists Born Great?02:22:51 The Artists Who Changed Rick Rubin02:31:50 Why Rick Rubin Made the Jay-Z Documentary02:42:18 Who Would You Thank?Follow Rick Rubin:Instagram - https://link.thediaryofaceo.com/2PaPSZIX - https://link.thediaryofaceo.com/88EVXdFYouTube - https://link.thediaryofaceo.com/HGY2CrIThe Way of Code - https://link.thediaryofaceo.com/CTcdN7DTetragrammaton - https://link.thediaryofaceo.com/vdp2ofThe Diary Of A CEO:◼ Join DOAC circle here - https://doaccircle.com/◼ Buy The Diary Of A CEO book here - https://link.thediaryofaceo.com/BWjLTZK◼ Shop The Diary Of A CEO collection: https://thediary.com/collections/shop◼ Get email updates - https://link.thediaryofaceo.com/5IB1H6E◼ Follow Steven - https://link.thediaryofaceo.com/AGU9QP4Sponsors:Ketone - https://ketone.com/STEVEN for 30% off your subscription orderFiverr - https://fiverr.com/diary and get 10% off your first order when you use code DIARY2 hr 49 min
- The New Way For Ordinary People To Build Wealth - Tony Robbins - #1153Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Tony Robbins is a life and business coach, entrepreneur and #1 New York Times Bestselling author.Christopher Zook is an investor, founder and chairman.How do you protect and grow your money when the markets feel so unpredictable? Tony Robbins has written extensively about money and investing, and he’s back with practical advice for everyday investors. So which strategies hold up in turbulent times, what costly mistakes should you avoid, and how can you make smarter decisions today to build a more secure financial future?Expect to learn the new strategies of investing from some of the nation's most successful funds, what Tony’s new philosophy and formula on investing is, which investing advice people still repeat today that is completely outdated, how normal people can get investing access to some of the world's fastest-growing companies, if we are in a genuine market bubble and much more…Sponsors:See discounts for all the products I use and recommend: https://chriswillx.com/dealsGet 160+ lab tests for just $365 and save an extra $25 at https://functionhealth.com/modernwisdomGet a free bottle of D3K2, an AG1 Welcome Kit, and more when you first subscribe at https://ag1.info/modernwisdomGet 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdomGet a Free Sample Pack of LMNT’s most popular flavours with your first purchase at https://drinklmnt.com/modernwisdomGet ChatGPT to explore ideas, solve problems, and learn faster at https://chatgpt.comTimestamps:(00:00) Tony’s Rules for Building Wealth(11:07) Is the S&P 500 Still a Smart Investment?(15:08) What Does Real Diversification Look Like?(20:03) The Investment Opportunities Everyone Overlooks(32:33) Which Investments Are Riskier Than They Seem?(36:09) Why Risk-Averse Investors Need More Diversification(41:22) How a Scarcity Mindset Shapes Your Investments(46:10) Can an Abundance Mindset Make You Reckless?(51:22) Why Everyone Needs a Dream Bucket(01:01:21) How Should Smart Investors Spend Their Money?(01:07:48) What Does the Future of AI Look Like?(01:22:13) How to Make Better Decisions(01:29:06) Where to Find TonyExtra Stuff:See me live in the UK & Ireland this October: https://chriswilliamson.liveGet my free reading list of 100 books to read before you die: https://chriswillx.com/booksTry my productivity energy drink Neutonic: https://neutonic.com/modernwisdomEpisodes You Might Enjoy:#577 - David Goggins - This Is How To Master Your Life: lnkfi.re/SN-Goggins#712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: lnkfi.re/SN-Peterson#700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: lnkfi.re/SN-Huberman-Get In Touch:Instagram: https://www.instagram.com/chriswillxTwitter: https://www.twitter.com/chriswillxYouTube: https://www.youtube.com/modernwisdompodcastEmail: https://chriswillx.com/contact-Learn more about your ad choices. Visit megaphone.fm/adchoices1 hr 31 min
- Alexander the Great — Mania for Subjugation (Part 3)Dan Carlin's Hardcore History: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Attacking the largest empire the world had ever seen is a huge endeavor at any age, but try doing it at 21. Alexander, fusing the qualities of a Napoleon with a gladiator, aims for immortality. The Persians are just in his way.4 hr 15 min
- The One-Skill-a-Year Plan for a More Interesting LifeArt of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------
We all have things we’ve always wanted to know how to do, but have never gotten around to learning. Speak a foreign language. Play an instrument. Write a book. Take up surfing. Maybe you’ve even started one of these pursuits a few times, only to drop it after a couple of weeks.
My guest calls this collection of abandoned or deferred desires your “invisible list” and is the author of a book of the same name.
Today on the show, Ravi Gupta presents a plan for tackling the things on your invisible list by picking one hobby-like activity each year and working your way to an intermediate level in it. He explains the different categories these pursuits can fall into, from the liftoff project to the mental marathon to the skillbatical, and how to pick the right one for your season of life. We also discuss how camps for grownups can make skill acquisition more enjoyable, why you should consider taking up an adult-appropriate sport like tennis, why Ravi decided to take the MCAT even though he doesn't plan to become a doctor, and how working on your invisible list can give your life chapters and, over the course of a decade, turn you into a Renaissance-man badass.
After the show is over, check out the show notes at aom.is/invisiblelist
0:00 — Introduction
1:45 — What is the Invisible List?
4:38 — Examples & Bucket List Comparison
8:46 — Why a Year Creates Life Chapters
11:10 — Making Time: Family & Constraints
15:44 — Five Rules of the Invisible List
18:39 — Why Aim for Intermediate?
21:19 — The Five Archetypes
26:50 — Liftoff Year: Powerlifting & Journaling
37:30 — Skill-Batical: Surfing & Adult Camps
43:17 — Age-Appropriate Sports: Tennis
45:46 — Mental Marathon: Taking the MCAT
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
1 hr - #433 How Michael Bloomberg WorksFounders: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------What I learned from reading Bloomberg by Michael Bloomberg.Made possible by:Ramp: https://ramp.comAppLovin: https://www.applovin.comVanta: https://vanta.com/foundersSage: https://founderspodcast.com/sage49 min
- Best Peptides, Stem Cells, Testosterone Exercise Hacks - Biohacking Roundtable - #1148Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this Biohacking Roundtable, we explore:What the best peptides for health & muscle building are.The latest biohacking tech that is real but sounds like science fiction.Which longevity supplements offer the most bang for your buck & are worth your time.The best diet and foods to eat to maximise longevity.and much more…Guests:Dr Gabrielle Lyon is a functional medicine physician and Founder of the Institute of Muscle-Centric Medicine.Ben Greenfield is a biohacker, coach, author, speaker, and Ironman Triathlete.Brigham Buhler is a healthcare entrepreneur, founder and CEO of Ways2Well, and co-founder of ReviveRx Pharmacy.Sponsors:See discounts for all the products I use and recommend: https://chriswillx.com/dealsGet 160+ lab tests for just $365 and save an extra $25 at https://functionhealth.com/modernwisdomGet up to 20% off Timeline’s leading longevity and cellular health supplement at https://timeline.com/modernwisdomGet up to $350 off the Eight Sleep Pod 5 at https://eightsleep.com/modernwisdomGet 10% discount on all Gymshark products at https://gym.sh/modernwisdom (use code MODERNWISDOM10)Get ChatGPT to explore ideas, solve problems, and learn faster at https://chatgpt.comTimestamps:(0:00) Science-Backed Peptide Regimes(6:47) The Health Hacks Scientists Actually Swear By(21:37) Do Heat Shock Proteins Really Matter?(24:02) Why Resonance Breathing Is So Powerful(27:17) Are MUSE Stem Cells the Next Big Breakthrough?(36:23) Are GLP-1s Causing Too Much Muscle Loss?(45:23) How GLP-1s Could Be Changing Desire(54:12) Why Has Testosterone Become So Demonised?(1:07:07) Should We Be Prioritising Testosterone?(1:12:43) The Fight Against the Peptide Ban(1:24:19) Health Freedom vs Protection: Where’s the Line?(1:29:37) Is Plasmapheresis the Next Longevity Breakthrough?(1:36:16) The Best Cost-Free Longevity Interventions(1:44:44) Is Proteinmaxxing Overhyped?(1:49:32) Is Fibre the Next Big Health Trend?(1:58:24) Inside Ben’s Longevity Diet(2:06:17) How Eating Speed Impacts GLP-1 Release(2:07:31) Does Fasting Actually Work?(2:10:28) Which Longevity Tools Are a Waste of Money?(2:20:54) Should Microplastics Be Listed on Packaging?(2:25:10) What’s the Next Big Biohacking Trend?(2:33:52) What is EMF Exposure Actually Doing to Us?(2:39:30) Do Air Scrubbers Actually Improve Your Health?(2:47:39) Should Everyone Get Genetic Testing?(2:49:49) Where to Find EveryoneExtra Stuff:See me live in the UK & Ireland this October: https://chriswilliamson.liveGet my free reading list of 100 books to read before you die: https://chriswillx.com/booksTry my productivity energy drink Neutonic: https://neutonic.com/modernwisdomEpisodes You Might Enjoy:#577 - David Goggins - This Is How To Master Your Life: lnkfi.re/SN-Goggins#712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: lnkfi.re/SN-Peterson#700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: lnkfi.re/SN-Huberman-Get In Touch:Instagram: https://www.instagram.com/chriswillxTwitter: https://www.twitter.com/chriswillxYouTube: https://www.youtube.com/modernwisdompodcastEmail: https://chriswillx.com/contact-Learn more about your ad choices. Visit megaphone.fm/adchoices2 hr 51 min
- #431 How Henry Singleton WorkedFounders: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------What I learned from reading Distant Force: A Memoir of the Teledyne Corporation and The Man Who Created It by George Roberts and The Outsiders by William Thorndike.Made possible by:Ramp: https://ramp.comApplovin: https://www.applovin.comVanta: https://vanta.com/foundersSome of my favorite quotes:0:00 — "He aggressively repurchased his stock, eventually buying over ninety percent of Teledyne's shares."0:45 — "He was known as The Sphinx for his reluctance to speak with either analysts or journalists."1:25 — Charlie Munger: "Singleton's financial returns were a mile higher than anyone else's, that they were utterly ridiculous."2:00 — Buffett: "The heads of many companies are not skilled in capital allocation. Their inadequacy is not surprising. Most bosses rise to the top because they've excelled in an area such as marketing, production, engineering, administration, or sometimes institutional politics."4:10 — Singleton: "Our conclusion was that the key was cash flow. Our attitude towards cash generation and asset management came out of our own thinking. It is not copied."4:30 — Buffett: "Henry Singleton has the best operating and capital deployment record in American business. If one took the hundred top business school graduates and made a composite of their triumphs, their record would not be as good as Singleton's."9:40 — Singleton: "If anyone wants to follow Teledyne, they should get used to the fact that our quarterly earnings will jiggle. Our accounting is set to maximize cash flow, not reported earnings."10:50 — Singleton believed buying stock at attractive prices was self-catalyzing, analogous to coiling a spring that at some future point would surge forward to realize full value."11:50 — Singleton: "I don't reserve any day-to-day responsibilities for myself, so I don't get into any particular rut. I do not define my job in any rigid terms, but in terms of having the freedom to do whatever seems to be in the best interest of the company at any time."14:35 — Singleton: "If everyone's doing them, there must be something wrong with them." (on share repurchases by Fortune 500 companies)26:30 — Singleton: "Teledyne is like a living plant, with our companies as the different branches and each putting out new branches and growing so that no one business is too significant."28:35 — Singleton: "We work our heads off to increase our own capability at collecting and promoting the right people. To the extent that we succeed, the whole company will succeed."32:30 — "What's unique about him is that I'll ask him a question about one of these companies that I've asked him to supervise, and he always knows the exact numerical answer. That's the kind of fellow that you pick who runs a company and does it well."35:00 — Singleton: "There are tremendous values in the stock market, but in buying stocks, not entire companies. Buying companies tends to raise the purchase price too high."41:35 — Claude Shannon on Singleton: "He always tries to work out the best moves, and maybe he doesn't like to talk too much because when you're playing a game, you don't tell anyone else what your strategy is."42:00 — Singleton: "We are not particularly persuaded by quick, temporary gains. We'd rather get something permanent, and that takes time."44:40 — Munger: "Henry Singleton was the smartest single human being I've ever known in my entire life."45:00 — Munger: "Henry was a lot smarter, but Warren had thought about investments a lot longer." (distinguishing raw intelligence from accumulated experience)0 min
- Doug Leone on Sequoia, Fear, Great Founders Starting Over at 69David Senra: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Doug Leone spent 26 years helping lead Sequoia Capital through successive eras of technological change. Born in Italy, he came to the United States without speaking English and carried the insecurity of an outsider into his career. That fear became fuel: whenever he felt himself falling behind, he forced himself to start over. After stepping down from Sequoia at 65 to make room for the next generation, he returned four years later. Now he considers himself a low-level analyst again, racing to understand an AI revolution that he believes is rewriting business more radically than anything he has seen before.Leone explains the three questions he asks before making an investment: Would he put his children's money into it? If he could make only 20 investments in his life, would this be one of them? Could it return the entire fund? He is interested only in extreme outliers—companies capable of returning 100 times the original investment—and says the biggest mistake venture investors make is selling their winners too early. Sequoia once owned enormous stakes in Apple, Cisco, Google and NVIDIA, but even the greatest investors failed to anticipate how long exceptional companies could continue compounding.His role as an investor is not to shape a founder's technology. It is to help turn a product into a business: recruiting the first team, building sales and marketing, navigating crucible moments and preserving the founder as the soul of the company. He describes backing David Vélez before Nubank existed, what Fred Luddy's unusual ServiceNow pitch revealed about him and why Sequoia looks for the same qualities in founders and its own partners: a hypercompetitive person with a heart of gold.Leone also discusses trust as the accelerant that makes business move quickly. Trust requires both competence and good intentions, and it is earned by helping founders when they are most vulnerable. He explains why founders should architect their boards as carefully as their products, why productive disagreement is different from argument and how to deliver difficult feedback so it can actually be heard. He closes with lessons from his longtime partner Michael Moritz: listen to the exact words people choose, put the other person first and always ask what a company could become if everything goes right.Show notes: https://www.davidsenra.com/episode/doug-leoneMade possible byRamp: https://ramp.comAppLovin: https://applovin.com/senraDeel: https://deel.com/senraChapters(00:00:00) How to Dominate for Decades(00:03:17) Turning Fear Into a Tailwind(00:05:40) Immigrant Drive, Hard Work & the Beach Club(00:12:19) Simplifying Life & Choosing Discomfort(00:14:37) The Homeless Sequoia Partner With No Plan B(00:16:49) Stepping Down, Coming Back & Starting Over(00:20:04) Why AI Is Different From Every Previous Technology Shift(00:22:13) Doug's Three Investment Heuristics(00:23:52) The Cost of Selling Great Companies Too Early(00:25:39) Helping Founders Turn Products Into Businesses(00:28:28) David Vélez, Nubank & the Psychology of Founder Support(00:32:25) Why Founders Must Remain the Soul of the Company(00:36:13) Torturing Yourself Into Greatness(00:39:57) Don Valentine, Succession & the Sequoia School of Hard Knocks(00:44:28) Staying Grounded & Developing a Sniffer for People(00:47:46) Hypercompetitive With a Heart of Gold(00:50:13) Fred Luddy, Israeli Founders & Radical Directness(00:52:28) Trust Is the Accelerant of Business(00:59:57) Starting From Zero & Hunting for the Next Great Founder(01:05:59) Architect Your Board Like Your Product(01:10:24) Truth, Disagreement & the Art of Difficult Feedback(01:13:43) Humanity, Introversion & the Value of Relationships(01:18:18) What Doug Learned From Michael MoritzLearn more about your ad choices. Visit megaphone.fm/adchoices1 hr 23 min
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