Amid a breakneck pace of regulatory changes under the Trump administration, healthcare stakeholders are scrambling to keep up. Experts are sharing learnings and doing their best to understand how the policies of today affect the sector.

Senior Writer Anastassia Gliadkovskaya chats with two executives with a front-row seat to those conversations: Maria Ghazal, CEO of the Healthcare Leadership Council; and Robert Andrews, CEO of the Health Transformation Alliance.

Both organizations recently had meetings with their members to debrief on policies like President Donald Trump’s One Big Beautiful Bill Act, Most Favored Nation and more.

To learn more about the topics in this episode: 

• White House announces new prescription drug website, TrumpRx
• How the shutdown impacts healthcare: Reductions in force begin at HHS, with some hiccups at CDC
• New Medicaid federal work requirements mean less leeway for states
• Federal government enters shutdown, virtual care programs expire

Note: Due to a recording glitch, Maria Ghazal's audio is slightly distorted early in the episode; it clears up shortly.

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Millions of Americans are affected by cancer each year. For many, hair loss is among the most distressing side effects of chemotherapy treatment, causing some to put off or refuse chemo.

A revolutionary technology exists: scalp cooling, which involves wearing a cold cap during treatment to restrict blood vessels and reduce how much chemo reaches the hair follicles.

Rossalynn Ripper, a breast cancer survivor, was able to use scalp cooling to prevent hair loss during her treatment. Now, she advocates for her home state of Maryland to pass a bill requiring insurers to cover the treatment.

Senior Writer Anastassia Gliadkovskaya talks to Ripper and her oncologist, Young Lee, M.D., of Luminis Health, about why scalp cooling is important to treatment access and what barriers remain.

To learn more about the topics in this episode: 

• CMS rolls out new payment model on improving cancer treatments
• Accelerating solutions to cancer through impact investing
• More patients are surviving cancer, but incident rates rising among women and younger adults: ACS report

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Payment integrity is top of mind as insurers face growing pressure to eliminate fraud, waste and abuse. Successful programs require investment in technology and expertise to analyze trends and identify abnormalities. The team at Optum Insight works closely with insurers across the healthcare system to examine this data

In this episode of "Podnosis," Fierce Healthcare senior writer Paige Minemyer sits down with Steve Yurjevich, CEO of the payer market at Optum Insight, to discuss the challenges and solutions in this space.

To learn more about the topics in this episode: 

• 'Well-intentioned, poorly executed waste': How tech companies aim to reduce billions in wasteful spending
• New Mountain Capital merges Apixio, Varis and The Rawlings Group in $3B deal
• CMS sets up real-time medical fraud center with DOGE; Federal contractor rolls out commercial tool
• Industry Voices—We need to fight fraud the right way

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The Democratic Women’s Caucus, a coalition of 96 lawmakers, advocates for women’s economic prosperity, healthcare access and safety.

In this week’s episode of "Podnosis," Fierce Healthcare staff writer Emma Beavins speaks with Rep. Teresa Leger Fernández of New Mexico and Rep. Kelly Morrison of Minnesota about their policy agenda, including the impact of Medicaid cuts, the fight for abortion and birth control access, and efforts to work with Republicans on healthcare reform.

To learn more about the topics in this episode: 

• Fighting maternal and infant health inequities
• UnitedHealth report: Disparities persist in maternal, infant health
• Most states saw hospital obstetric service shutdowns from 2010-2022, with rural states hit hardest
• Gates Foundation invests $2.5B to spark women's health innovations
• The business case for investing in women’s health
• CMS selects states for Medicaid maternal health model
• Maternal mental health in the spotlight

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Lawmakers are turning up the heat on pharmacy benefit managers, with more than 1,500 bills introduced this year targeting drug costs, utilization rules and pharmacy networks. In the latest episode of Podnosis, Wes Hill, senior director at RxBenefits, said rising drug prices and pressure from constituents are driving the surge. While federal movement has been limited, states are advancing legislation at a rapid pace, creating new compliance challenges for PBMs and plan sponsors.

Hill said employers—who shoulder much of the cost of pharmacy benefits—need to make their voices heard. By tracking legislation, assessing its impact and working with advisors, they can help shape reforms and protect their health plans. To hear more about the legal battles and what’s ahead for PBMs, listen to the full Podnosis episode.

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Medication nonadherence is not new, but it remains a persistent, complex problem. Adherence rates hover near 50%—roughly the same as two decades ago—as companies explore new ways to engage patients and help them stick to treatment regimens.

AdhereHealth combines technology with care navigators to identify at-risk patients and help them consistently access their prescriptions.

In this episode of "Podnosis," Fierce Healthcare Senior Writer Anastassia Gliadkovskaya speaks with Chandra Y. Osborn, Ph.D., M.P.H., chief experience officer at AdhereHealth, about how the company takes on risk to drive outcomes and why it keeps a human in the loop.

To learn more about the topics in this episode: 

• Healthcare 'flying blind': Medication nonadherence and how remote therapeutic monitoring can help
• Out-of-pocket spending on prescriptions grew even after accounting for rebates: study
• PatchRx to integrate medication adherence data with virtual care platforms
• Scriptology acquires RxLive to build out its tech stack

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What are the main challenges hospitals face today? And how can they begin to get their arms around them while centering patients in their decision making? 

In this episode of "Podnosis," Senior Writer Anastassia Gliadkovskaya speaks to Janina Beilner, SVP of healthcare at Siemens, about how the company helps hospitals use technology in a thoughtful way to improve their infrastructure, operations and ultimately the patient experience. 

To learn more about the topics in this episode: 

• How health systems are reshaping their strategies in the face of federal policy uncertainty
• Human-centered design in healthcare
• How Nvidia-backed Artisight is taking smart hospitals to the next level with AI and computer vision
• Breathing better: Hospitals begin to phase out major pollutants in patient care

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Hope, when applied with purpose and action, can be a powerful force for driving change in healthcare.

That’s the philosophy of Eugene Woods, CEO of Advocate Health and a 2025 Fierce 50 honoree, who joins Ayla Ellison, Editor-in-Chief of Fierce Life Sciences & Healthcare, to share how he puts “Applied Hope” into practice. Woods explains how this approach combines optimism with action and why it’s become a guiding strategy for one of the nation’s largest nonprofit health systems.

In their conversation, Woods discusses leading through massive organizational change, cultural transformation and the rapid adoption of new technologies. He offers insights on improving quality and affordability, investing in both rural communities and urban neighborhoods and preparing for a future shaped by AI and more human-centered healthcare delivery.

To learn more about the topics in this episode: 

• Fierce 50 of 2025 

• Eugene A. Woods—Fierce 50 Leadership Honoree 

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Corporate venture capital is gaining traction across industries. From 2014 to 2024, it accounted for nearly half of all VC deal value. Healthcare is no exception: dozens of health systems now have venture arms or invest directly in healthcare startups.

Arizona-based Banner Health is one of them, taking a strategic approach to equity deals and joint ventures. To unpack that strategy, Senior Writer Anastassia Gliadkovskaya spoke with Mark Garvin, former senior vice president of partnership and venture development at Banner Health.

This episode was recorded before Garvin departed from Banner. He no longer represents the organization, but his insights remain highly relevant.

To learn more about the topics in this episode: 

• Banner Health boosts investment in AI-powered automation tech to maximize operating rooms
• What’s next for digital health investing in 2025?
• Ardent Health execs eye outpatient expansion, see nonprofits' headwinds as growth opportunity

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Transitions of care—moving patients from one care site to another—continue to be a major challenge in healthcare. Nearly 1 in 5 Medicare patients discharged from a hospital—approximately 2.6 million seniors—are readmitted within 30 days, at a cost of more than $26 billion every year, according to the Centers for Medicare & Medicaid Services.

Salman Ali, CEO and co-founder of Kouper, saw opportunities to take a tech-based approach to care transitions, using generative AI to ensure patients don’t fall through the cracks after hospital discharge. As executive-in-residence at venture capital group General Catalyst, Stephen Klasko, M.D., has a front-row seat to the latest innovations in AI. And as former CEO of Jefferson Health in Philadelphia, Klasko understands the value of using technology to tackle operational pain points at health systems.

In this episode of “Podnosis,” Ali and Klasko dig into Kouper’s approach to improving care transitions and why they see AI at a true inflection point. They talk about how hospitals can deploy AI without adding to staff burden and why trust matters more than technology in winning over health system leaders.

To learn more about the topics in this episode: 

• Kouper is tackling transitions of care armed with $10M from General Catalyst, 25Madison and CVS' venture arm
• Ohio attorney general approves sale of Summa Health to General Catalyst's HATCo, with some conditions
• Commure raises $200M in growth financing from General Catalyst

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