Aging published this high-scoring research paper on July 30, 2019, entitled, “Effects of transcutaneous vagus nerve stimulation in individuals aged 55 years or above: potential benefits of daily stimulation,” by researchers from the United Kingdom’s University of Leeds and University of Glasgow.

In 2019, the researchers reported on the results of the effects of tVNS among participants 55 years of age and older in three studies.

In the first study, they observed the effects of acute, single-session tVNS on cardiovascular autonomic function compared with the effects of sham (ear lobe/placebo) stimulation among 14 healthy participants 55 years of age and older. They collected baseline values and measured heart rate variability (HVR) and baroreflex sensitivity.

“Since not all participants responded to tVNS, we examined if it was possible to identify potential tVNS responders from baseline parameters.”

In the second study, the researchers explored the effects of acute, single-session tVNS on autonomic function in the same age group by expanding the sample to 51 participants. The third study examined 26 participants in the same age group when administered tVNS once per day, for 15-minutes, over the course of two weeks. The researchers reported the impacts of daily tVNS in measures of autonomic function, health-related quality of life (QoL), mood, and sleep.

“Transcutaneous vagal nerve stimulation (tVNS) acutely administered to the tragus in healthy volunteers aged ≥ 55 years was associated with improvements in spontaneous cardiac baroreflex sensitivity and HRV.”

To date, this study has generated an Altmetric Attention Score of 350. The Altmetric Attention Score provides an at-a-glance indication of the volume and type of online attention the research has received.

Top Aging publications rated by Altmetric Attention Score - https://www.aging-us.com/news_room/altmetric

Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.102074

DOI - https://doi.org/10.18632/aging.102074

Full text - https://www.aging-us.com/article/102074/text

Correspondence to: Jim Deuchars email: [email protected]

Keywords: vagus nerve stimulation, autonomic nervous system, neuromodulation, quality of life, mood, aging

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Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

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