The Biotech Startups Podcast

🧬 Rafael Rosengarten - Part 1 | From Salt Marsh to Biotech CEO | Snorkeling into Science | Choosing Marine Biology Over Cooking on a Mediterranean Yacht


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Part 1 of 4: My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI.
Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics.
In this episode, you'll hear about:

  • Rafael's upbringing in rural South Carolina, influenced by his parents' intellectual hippie activist background and nature
  • How his French cell biologist uncle sparked his love for science through snorkeling 
  • Rafael's journey at Dartmouth, initially pursuing chemistry but ultimately finding his passion in evolutionary biology and ecology
  • His post-college experiences alternating between scientific research and culinary pursuits
  • The pivotal decision to attend a marine biology program at Friday Harbor instead of accepting an offer to cook on a private yacht

If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening!
Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/https://www.genialis.com/ 
Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.com
Excedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ 
Enriched Notes: 

Topics Mentioned:Dartmouth https://home.dartmouth.edu/ Bay Wolf https://www.berkeleyside.org/2015/07/01/oaklands-bay-wolf-restaurant-closing-after-40-years Yale https://www.yale.edu/ Chez Panisse https://www.chezpanisse.com/1/ Friday Harbor Laboratories https://fhl.uw.edu/ 
People Mentioned:Jay Keasling https://www.linkedin.com/in/jay-keasling-6783754/ Mark McPeak https://biology.dartmouth.edu/people/mark-alan-mcpeek David Peart https://www.linkedin.com/in/david-peart-251787302/ Carol Folt https://biology.dartmouth.edu/people/carol-l-folt Leo Buss https://eeb.yale.edu/people/faculty/leo-buss Alice Waters https://en.wikipedia.org/wiki/Alice_Waters Fanny Singer (Waters) https://thefoldmag.com/arts-culture/a-conversation-with-fanny-singer-about-her-mother-daughter-memoir-always-home Jeremiah Tower https://www.linkedin.com/in/jeremiah-tower/ Dan Barber https://en.wikipedia.org/wiki/Dan_Barber Thomas Keller https://en.wikipedia.org/wiki/Thomas_Keller 
Timestamps:00:49 Intro02:48 Rafael's upbringing in rural South Carolina and early influences05:50 Discussing the impact of Rafael's upbringing on his business philosophy07:44 Rafael's decision to attend Dartmouth College10:27 Family influence on Rafael's academic pursuits12:04 Rafael's experiences at Dartmouth and choosing his major14:30 Summer internship at Bay Wolf restaurant in Oakland16:55 Influential professors and classmates at Dartmouth18:22 Post-graduation experiences and working at Yale23:20 Comparing cooking experiences on the West Coast and East Coast26:38 Entering Yale's biomedical program and the Friday Harbor experience29:48 OutroThe Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.
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