ReSay

This article "High-resolution imaging mass cytometry to map subcellular structures" is published in Nature.

Author:⁠⁠ Alina Bollhagen

Journal: Nature

Year: 2025

Podcast type: Short

Authors are:

• Alina Bollhagen
• Viola Heinzelmann-Schwarz
• Francis Jacob
• James Whipman
• Ricardo Coelho
• Bernd Bodenmiller

Affiliations:

Alina Bollhagen, Bernd Bodenmiller ,Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland

James Whipman1,Alina Bollhagen, Bernd Bodenmiller , Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland

Alina Bollhagen, Life Science Zurich Graduate School, ETH Zurich and University of Zurich, Zurich, Switzerland

Viola Heinzelmann-Schwarz,Ricardo Coelho, Francis Jacob, Ovarian Cancer Research, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland

Viola Heinzelmann-Schwarz, Gynecologic Cancer Center, University Hospital Basel, Basel, Switzerland

This article "When Models Manipulate Manifolds: The Geometry of a Counting Task" is published in Anthropic research report.

Author:⁠⁠ Wes Gurnee

Journal: Anthropic research report

Year: 2025

Podcast type: Short

The authors are:

• Wes Gurnee
• Emmanuel Ameisen
• Isaac Kauvar
• Julius Tarng
• Adam Pearce
• Chris Olah
• Joshua Batson

Affiliations:

Wes Gurnee, Emmanuel Ameisen, Isaac Kauvar, Julius Tarng, Adam Pearce, Chris Olah, Joshua Batson, Anthropic

This article "Nonlinear dynamics of multi-omics profiles during human aging" is published in Nature Aging.

Author:⁠⁠ Xiaotao Shen

Journal: Nature Aging

Year: 2024

Podcast type: Article

The authors are:

• Xiaotao Shen
• Daniel Hornburg
• Chuchu Wang
• Xin Zhou
• Si Wu
• Michael P. Snyder
• Wenyu Zhou

Affiliations:

Xiaotao Shen, Xin Zhou, Si Wu, Michael P. Snyder, Wenyu Zhou ,Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA

Daniel Hornburg ,Institute for Biomedicine, Eurac Research, Bolzano, Italy ,Department of Biomedical Informatics, Harvard Medical School, Harvard University, Boston, MA, USA, Broad Institute of MIT and Harvard, Cambridge, MA, USA

Chuchu Wang ,Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA, Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA

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This article " Multi-omic profiling reveals age-related immune dynamics in healthy adults" is published in Nature.

Author: Qiuyu Gong

Journal: Nature

Year: 2025

Podcast type: Short

Authors are:

• Qiuyu Gong
• Mehul Sharma
• Marla C. Glass
• Emma L. Kuan
• Aishwarya Chander
• Mansi Singh
• Lucas T. Graybuck
• Zachary J. Thomson
• Christian M. LaFrance
• Samir Rachid Zaim
• Tao Peng
• Lauren Y. Okada
• Palak C. Genge
• Katherine E. Henderson
• Elisabeth M. Dornisch
• Erik D. Layton
• Peter J. Wittig
• Alexander T. Heubeck
• Nelson M. Mukuka
• Julian Reading
• Garrett Strawn
• Teminijesu Titus-Adewunmi
• Kathleen Abadie
• Charles R. Roll
• Veronica Hernandez
• Vaishnavi Parthasarathy
• Tyanna J. Stuckey
• Blessing Musgrove
• Elliott Swanson
• Cara Lord
• Morgan D. A. Weiss
• Cole G. Phalen
• Regina R. Mettey
• Kevin J. Lee
• John B. Johanneson
• Erin K. Kawelo
• Jessica Garber
• Upaasana Krishnan
• Megan Smithmyer
• E. John Wherry
• Laura A. Vella
• Sarah E. Henrickson
• Mackenzie S. Kopp
• Adam K. Savage
• Lynne A. Becker
• Paul Meijer
• Ernest M. Coffey
• Jorg J. Goronzy
• Mikael Sigvardsson
• Cate Speake
• Thomas F. Bumol
• Ananda W. Goldrath
• Troy R. Torgerson
• Xiao-jun Li
• Peter J. Skene
• Jane H. Buckner
• Claire E. Gustafson

This article "Spatiotemporal dynamics of the cardioimmune niche during lesion repair" is published in Nature.

Author: Andy Shing-Fung Chan

Journal: Nature

Year: 2025

Podcast type: Short

Authors are:

⦁ Andy Shing-Fung Chan

⦁ Joachim Greiner

⦁ Lisa Marschhäuser

⦁ Tomás A. Brennan

⦁ Stefanie Perez-Feliz

⦁ Ankit Agrawal

⦁ Helene Hemmer

⦁ Katrin Sinning

⦁ Jennifer Wing Lam Cheung

⦁ Zafar Iqbal

⦁ Alexander Klesen

⦁ Tamara Antonela Vico

⦁ Julieta Aprea

⦁ Ingo Hilgendorf

⦁ Thomas Seidel

⦁ Martin Vaeth

⦁ Eva A. Rog-Zielinska

Affiliations:

Andy Shing-Fung Chan, Lisa Marschhäuser, Ankit Agrawal, Helene Hemmer, Katrin Sinning, Jennifer Wing Lam Cheung, Martin Vaeth, Eva A. Rog-Zielinska, Würzburg Institute of Systems Immunology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany

Joachim Greiner, Tomás A. Brennan, Stefanie Perez-Feliz, Alexander Klesen, Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, University Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany

Zafar Iqbal, Thomas Seidel, Institute of Cellular and Molecular Physiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany

Alexander Klesen, Department of Congenital Heart Defects and Paediatric Cardiology, University Heart Center Freiburg-Bad Krozingen, University Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany

Tamara Antonela Vico, Ingo Hilgendorf, Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, University Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany

Julieta Aprea, DRESDEN-concept Genome Center, c/o CMCB Center for Molecular and Cellular Bioengineering, Technology Platform of the TUD Dresden University of Technology, Dresden, Germany

Eva A. Rog-Zielinska, CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany

Eva A. Rog-Zielinska, CAIDAS - Center for Artificial Intelligence and Data Science, Julius-Maximilians-Universität Würzburg, Würzburg, Germany

This article "Myeloid cells mediate interferon-driven resistance to immunotherapy in advanced renal cell carcinoma" is published in Immunity.

Author: Kevin Bi

Journal: Immunity

Year: 2025

Podcast type: Short

Authors are:

⦁ Kevin Bi

⦁ Soki Kashima

⦁ Sabrina Y. Camp

⦁ Kevin Meli

⦁ Eddy Saad

⦁ Breanna M. Titchen

⦁ Chris Labaki

⦁ Ziad Bakouny

⦁ Erica M. Pimenta

⦁ Jihye Park

⦁ Erin Shannon

⦁ Jingxin Fu

⦁ Sherin Xirenayi

⦁ Jack Horst

⦁ Lotus Lum

⦁ Jeffrey J. Ishizuka

⦁ Toni K. Choueiri

⦁ David A. Braun

⦁ Eliezer M. Van Allen

Affiliations:

Kevin Bi, Sabrina Y. Camp, Kevin Meli, Eddy Saad, Breanna M. Titchen, Chris Labaki, Erica M. Pimenta, Jihye Park, Erin Shannon, Jingxin Fu, Sherin Xirenayi, Eliezer M. Van Allen, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA

Kevin Bi, Sabrina Y. Camp, Kevin Meli, Eddy Saad, Breanna M. Titchen, Chris Labaki, Erica M. Pimenta, Jihye Park, Erin Shannon, Jingxin Fu, Sherin Xirenayi, Eliezer M. Van Allen, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA

Soki Kashima, Jeffrey J. Ishizuka, Toni K. Choueiri, David A. Braun, Center for Molecular and Cellular Oncology, Department of Medicine (Oncology), Yale School of Medicine, New Haven, CT, USA

Soki Kashima, Department of Urology, Akita University School of Medicine, Akita, Japan

Kevin Meli, Breanna M. Titchen, Division of Medical Sciences PhD Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA, USA

Chris Labaki, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Ziad Bakouny, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Sherin Xirenayi, Systems, Synthetic, and Quantitative Biology Graduate Program, Harvard University, Cambridge, MA, USA

Lotus Lum, Jeffrey J. Ishizuka, Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA

Jeffrey J. Ishizuka, Department of Pathology, Yale School of Medicine, New Haven, CT, USA

David A. Braun, Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA

This article " Deep generative modeling of sample-level heterogeneity in single-cell genomics" is published in Nature.

Author: Pierre Boyeau

Journal: Nature

Year: 2025

Podcast type: Short

Authors are:

• Pierre Boyeau
• Justin Hong
• Adam Gayoso
• Martin Kim
• José L. McFaline-Figueroa
• Michael I. Jordan
• Elham Azizi
• Can Ergen
• Nir Yosef

Affiliations:

Pierre Boyeau,Martin Kim,Michael I. Jordan,Can Ergen,Nir Yosef,University of California, Berkeley, CA, USA

Justin Hong,José L. McFaline-Figueroa,Elham Azizi,Columbia University, New York, NY, USA

Justin Hong,José L. McFaline-Figueroa,Elham Azizi,Irving Institute for Cancer Dynamics,

Columbia University, New York, NY, USA

José L. McFaline-Figueroa,Elham Azizi,Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA

José L. McFaline-Figueroa,Elham Azizi,Department of Biomedical Engineering, Columbia University, New York, NY, USA

Adam Gayoso,Michael I. Jordan,Can Ergen,Nir Yosef,Center for Computational Biology, University of California, Berkeley, CA, USA

Michael I. Jordan,Department of Statistics, University of California, Berkeley, CA, USA

Nir Yosef, Weizmann Institute of Science, Rehovot, Israel

This article "Lymphoid gene expression supports neuroprotective microglia function" is published in Nature.

Author: Pinar Ayata

Journal: Nature

Year: 2025

Podcast type: Short

The authors are:

⦁ Pinar Ayata

⦁ Jessica M. Crowley

⦁ Matthew F. Challman

⦁ Vinaya Sahasrabuddhe

⦁ Maud Gratuze

⦁ Sebastian Werneburg

⦁ Diogo Ribeiro

⦁ Emma C. Hays

⦁ Violeta Durán-Laforet

⦁ Travis E. Faust

⦁ Philip Hwang

⦁ Francisco Mendes Lopes

⦁ Chrysa Nikopoulou

⦁ Sarah Buchholz

⦁ Robert E. Murphy

⦁ Taoyu Mei

⦁ Anna A. Pimenova

⦁ Carmen Romero-Molina

⦁ Francesca Garretti

⦁ Tulsi A. Patel

⦁ Claudia De Sanctis

⦁ Angie V. Ramirez Jimenez

⦁ Megan Crow

⦁ Felix D. Weiss

⦁ Jason D. Ulrich

⦁ Edoardo Marcora

⦁ John W. Murray

⦁ Felix Meissner

⦁ Andreas Beyer

⦁ Dan Hasson

⦁ John F. Crary

⦁ Dorothy P. Schafer

⦁ David M. Holtzman

⦁ Alison M. Goate

⦁ Alexander Tarakhovsky

⦁ Anne Schaefer

Affiliations:

Pinar Ayata, Jessica M. Crowley, Matthew F. Challman, Vinaya Sahasrabuddhe, Diogo Ribeiro, Emma C. Hays, Philip Hwang, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Edoardo Marcora, John F. Crary, Alison M. Goate, Anne Schaefer ,Nash Family Department of Neuroscience, Department of Psychiatry, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Pinar Ayata, Anna A. Pimenova, Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Claudia De Sanctis, Edoardo Marcora, John F. Crary, Alison M. Goate, Anne Schaefer,Ronald M. Loeb Center for Alzheimer’s Disease, Center for Glial Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Pinar Ayata,Neuroscience Initiative, Advanced Science Research Center, Graduate Program in Biology, Graduate Program in Biochemistry, Graduate Program in Neuroscience, The City University of New York Graduate Center, New York, NY, USA.

Maud Gratuze, Jason D. Ulrich, David M. Holtzman,Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.

Maud Gratuze,Institute of Neurophysiopathology (INP), University of Aix-Marseille, CNRS UMR 7051, Marseille, France.

Sebastian Werneburg, Violeta Durán-Laforet, Travis E. Faust, Robert E. Murphy, Dorothy P. Schafer,Department of Neurobiology, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Sebastian Werneburg,Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, Michigan Neuroscience Institute, Department of Molecular & Integrative Physiology, University of Michigan, Michigan Medicine, Ann Arbor, MI, USA.

Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Anne Schaefer,Max Planck Institute for Biology of Ageing, Cologne, Germany.

Francisco Mendes Lopes, Chrysa Nikopoulou, Sarah Buchholz, Taoyu Mei, Andreas Beyer,Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

Taoyu Mei, Andreas Beyer,Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.

Carmen Romero-Molina, Francesca Garretti, Tulsi A. Patel, Edoardo Marcora, Alison M. Goate,Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Claudia De Sanctis, John F. Crary,Department of Pathology, Department of Artificial Intelligence & Human Health, Neuropathology Brain Bank and Research CoRE, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Angie V. Ramirez Jimenez, Dan Hasson,Bioinformatics for Next-Generation Sequencing (BiNGS) Core, Tisch Cancer Institute, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Megan Crow,Department of Human Genetics, Genentech Inc., South San Francisco, CA, USA.

This article "Site-specific DNA insertion into the human genome with engineered recombinases" is published in Nature Biotechnology.

Author: Alison Fanton

Journal: Nature Biotechnology

Year: 2025

Podcast type: Short

The authors are:

⦁ Alison Fanton

⦁ Liam J. Bartie

⦁ Juliana Q. Martins

⦁ Vincent Q. Tran

⦁ Laine Goudy

⦁ Courtney Kernick

⦁ Matthew G. Durrant

⦁ Jingyi Wei

⦁ Zev Armour-Garb

⦁ April Pawluk

⦁ Silvana Konermann

⦁ Alexander Marson

⦁ Luke A. Gilbert

⦁ Theodore L. Roth

⦁ Patrick D. Hsu

Affiliations:

Alison Fanton, Liam J. Bartie, Juliana Q. Martins, Vincent Q. Tran, Laine Goudy, Courtney Kernick, Matthew G. Durrant, Jingyi Wei, April Pawluk, Silvana Konermann, Alexander Marson, Luke A. Gilbert, Theodore L. Roth, Patrick D. Hsu

Arc Institute, Palo Alto, CA, USA

Alison Fanton, Patrick D. Hsu

Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA ,University of California, Berkeley − University of California, San Francisco, Graduate Program in Bioengineering, Berkeley, CA, USA

Juliana Q. Martins ,Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA

Vincent Q. Tran ,Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA

Laine Goudy, Zev Armour-Garb, Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA

Laine Goudy, Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA

Courtney Kernick, Theodore L. Roth ,Department of Pathology, Stanford University, Stanford, CA, USA

Silvana Konermann ,Department of Bioengineering, Stanford University, Stanford, CA, USA

Alexander Marson, Department of Biochemistry, Stanford University, Stanford, CA, USA

Luke A. Gilbert ,Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA, Department of Urology, University of California, San Francisco, San Francisco, CA, USA

Patrick D. Hsu ,Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA

This article "TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages" is published in Nature Genetics.

Author: Ana Henriques

Journal: Nature Genetics

Year: 2025

Podcast type: Short

The authors are:

⦁ Ana Henriques

⦁ Maria Salvany-Celades

⦁ Paula Nieto

⦁ Sergio Palomo-Ponce

⦁ Marta Sevillano

⦁ Xavier Hernando-Momblona

⦁ Emily Middendorp-Guerra

⦁ Montserrat Llanses Martinez

⦁ Elisabeth Marjolein Haak

⦁ Juan Nieto

⦁ Ginevra Caratú

⦁ Domenica Marchese

⦁ Max Ruiz Gil

⦁ Sebastien Tosi

⦁ Theresa Suckert

⦁ Jordi Badia-Ramentol

⦁ Adrià Caballé-Mestres

⦁ Carolina Sanchez-Zarzalejo

⦁ Lidia Mateo

⦁ Daniele V. F. Tauriello

⦁ Antoni Riera

⦁ Elena Sancho

⦁ Camille Stephan-Otto Attolini

⦁ Alejandro Prados

⦁ Holger Heyn

⦁ Eduard Batlle

Affiliations:

Ana Henriques, Maria Salvany-Celades, Sergio Palomo-Ponce, Marta Sevillano, Xavier Hernando-Momblona, Emily Middendorp-Guerra, Montserrat Llanses Martinez, Elisabeth Marjolein Haak, Sebastien Tosi, Jordi Badia-Ramentol, Adrià Caballé-Mestres, Carolina Sanchez-Zarzalejo, Lidia Mateo, Daniele V. F. Tauriello, Antoni Riera, Elena Sancho, Camille Stephan-Otto Attolini, Alejandro Prados, Eduard Batlle, Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain

Paula Nieto, Juan Nieto, Ginevra Caratú, Domenica Marchese, Max Ruiz Gil, Holger Heyn, CNAG-CRG, Centre for Genomic Regulation, Barcelona, Spain