SHR # 2354 :: RLRx: Testosterone Replacement Plus Exercise Reverses Heart Pathology in Type 2 Diabetes Study Shows : Adam Lamb - Angiogenesis is a naturally occurring physiological phenomenon that increases vascularization of the heart. It is well known that it is shut off in the Type 2 Diabetic individual leading to heart pathologies that increase the risk of heart attack. This study showed that exercise alone doesn't improve angiogenesis and it takes testosterone to turn on micro RNA machinery that increases new vascularization of the heart.