The Hormone Genius Podcast

S5 Ep. 29: Estrogen Dominance and Surprising Role of Your Gut and Liver in Hormone Health


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Do you have heavy periods, feel bloated, have headaches, bad PMS, or struggle with infertility and/or fibroids?
Have you ever considered that these symptoms—and many more—could be related to a hormone imbalance?
Estrogen dominance is one of the most commonly misunderstood hormone issues. In this episode, we take a deep dive into what estrogen dominance actually means.
We explore the critical role of your liver and gut in estrogen detoxification and how dysfunction in these systems can lead to symptoms like heavy periods, breast tenderness, anxiety, fatigue, and stubborn weight gain. You'll learn how your liver goes through a two-phase detox process to neutralize estrogen, and how the gut's microbiome—including the estrobolome—can either help or hinder that elimination process.
We also unpack a lesser-known but powerful enzyme called beta-glucuronidase, which can cause estrogen that was supposed to be excreted to be reabsorbed back into the body—essentially recycling hormones and contributing to estrogen dominance. This often happens when gut health is compromised due to dysbiosis, constipation, or poor diet.
Whether you're in your reproductive years, navigating perimenopause, this episode will help you better understand the physiology behind estrogen dominance and how to begin addressing it at the root.
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Medical disclaimer: The information presented in The Hormone Genius Podcast is for informational purposes only and is not intended to be a substitute for actual medical or mental health advice from a doctor, psychologist, or any other medical or mental health professional.
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The Hormone Genius PodcastBy Teresa Kenney and Jamie Rathjen

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