Entering the field of medicine is often filled with excitement and a sense of purpose. The prospect of healing and making a difference in people's lives can be exhilarating. However, as many healthcare professionals can relate, the reality of working in medicine can also lead to burnout and a loss of connection to one's initial motivations. Nearing the end of their third year of residency, in S6E14, Margaux, Leen, and Harjit revisit the complexities of burnout, and talk candidly and honestly about the challenges they have faced—and continue to face—in their medical careers.