Madeleine Finlay is joined by Ian Sample, the Guardian’s science editor and Science Weekly co-host, to answer the questions we are all asking about Covid this autumn, from what is going on with the new variant XEC to how to get a vaccine and what scientists think the government should be doing differently. Help support our independent journalism at theguardian.com/sciencepod

Just before Britain’s last coal-fired power station, Ratcliffe-on-Soar, powered down for the final time, Madeleine Finlay travelled to Nottinghamshire with energy correspondent Jillian Ambrose for a last tour of the site. Britain is the first major economy to move away from coal entirely as it strives to meet the target of net zero by 2030. Jillian and Madeleine speak to employees to find out what working at the plant has meant to them, and how they’re feeling as the closing date approaches. Help support our independent journalism at theguardian.com/sciencepod

Industrial civilisation is close to breaching a seventh planetary boundary, and may already have crossed it, according to scientists who have compiled the latest report on the state of the world’s life-support systems. They say ocean acidification is close to critical threshold, posing a threat to marine ecosystems and global liveability. Ian Sample speaks to Prof Helen Findlay, a biological oceanographer at the Plymouth Marine Laboratory, to find out why the oceans have reached this state, and whether there is anything we can do to reverse the damage.. Help support our independent journalism at theguardian.com/sciencepod

Madeleine Finlay speaks to Dr Saul Newman, an interdisciplinary researcher at University College London and the University of Oxford, who has just won an Ig Nobel prize – given to scientific research that ‘first makes people laugh, and then makes them think’ – for his work showing that many claims of people living extraordinarily long lives come from places with short lifespans, no birth certificates, and where clerical errors and pension fraud abound. He tells Madeleine what happened when he went looking for the world’s centenarians, and how his work has been received by the longevity research community. Help support our independent journalism at theguardian.com/sciencepod

In a special episode recorded live at the British Science Festival, Madeleine Finlay and guests explore the question: will AI make a good companion? AI could give us new ways to tackle difficult problems, from young people’s mental health issues to isolation in care homes. It also raises challenging questions about the increasing role of tech in our personal lives. To explore these questions, Madeleine is joined by the Guardian’s science editor, Ian Sample; Tony Prescott, a professor of computational robotics at Sheffield University; and Dr Mhairi Aitken, an ethics fellow at the Alan Turing Institute and visiting senior lecturer at Queen Mary University of London.. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample talks to Dr Laura Pritschet, a postdoctoral fellow of psychiatry at the University of Pennsylvania, about her research using precision scans to capture the profound changes that sweep across the brain during pregnancy. She explains what this new work reveals about how the brain is reorganised in this period, whether it could it help us better understand conditions like pre-eclampsia and postnatal depression, and why women’s brains have often been overlooked by neuroscience. And neuroscientist Dr Liz Chrastil whose brain was scanned, explains what the experience was like. Help support our independent journalism at theguardian.com/sciencepod

They were developed as diabetes drugs, then their potential for promoting significant weight loss became apparent. And now study after study seems to suggest that drugs such as Ozempic and Wegovy could have all sorts of health benefits, leading some scientists to hail them a breakthrough that could transform many chronic diseases of ageing. But what’s the mechanism for these effects and is it caused by more than weight loss? The Guardian’s science correspondent Nicola Davis tells Madeleine Finlay what is known so far. Help support our independent journalism at theguardian.com/sciencepod

Ian Sample and science correspondent Hannah Devlin discuss some of the science stories that have made headlines this week, from a new technique that uses food colouring to make skin transparent, to the first case of bird flu in a person with no known contact with sick animals, and a study looking at premature brain ageing in young people during Covid. Help support our independent journalism at theguardian.com/sciencepod

Environment editor Damian Carrington tells Madeleine Finlay about his recent trip to Greenland on board a ship with a group of intrepid scientists. They were on a mission to explore the maelstrom beneath Greenland’s glaciers, an area that has never been studied before, and were hoping to find answers to one of the world’s most pressing questions – how quickly will sea levels rise?. Help support our independent journalism at theguardian.com/sciencepod

Last month the World Health Organization declared the recent mpox outbreak that began in the Democratic Republic of the Congo a public health emergency of international concern. As scientists race to find out more about the new strain, Ian Sample talks to Trudie Lang, professor of global health research and director of the global health network at the University of Oxford, to find out what we still need to learn in order to tackle and contain the virus. Help support our independent journalism at theguardian.com/sciencepod