Scream VI is a 2023 American slasher film directed by Matt Bettinelli-Olpin and Tyler Gillett, and written by James Vanderbilt and Guy Busick. It is the sequel to Scream (2022) and the sixth installment in the Scream film series. The film stars Melissa Barrera, Jasmin Savoy Brown, Mason Gooding, Jenna Ortega, Hayden Panettiere, and Courteney Cox, all reprising their roles from previous installments, alongside Jack Champion, Henry Czerny, Liana Liberato, Dermot Mulroney, Devyn Nekoda, Tony Revolori, Josh Segarra, and Samara Weaving. Scream VI follows a new Ghostface killer who targets the surviving members of the "Woodsboro legacy attacks" in New York City.  

Like its predecessors, the film combines the violence of the slasher genre with elements of black comedy and a "whodunit" mystery, and satirizes the trends of film franchises and subversion of audience expectations. Film series star Neve Campbell announced she would not be returning as Sidney Prescott because she felt the offer presented to her was unacceptable, making this the first film in the series not to feature the character. 

 Scream VI premiered at the AMC Lincoln Square Theater in Manhattan on March 6, 2023, and was theatrically released in the United States on March 10 by Paramount Pictures. The film received generally positive reviews from critics, who praised the kills and performances.