Highlights from the February 3rd issue of CMAJ, presented by Dr. John Fletcher, editor-in-chief, and Dr. Ken Flegel, senior editor. In this issue: HPV vaccination and its effects on sexual behaviour in adolescent girls, and discovery of a founder mutation for congenital sucrase-isolmaltase deficiency in an Inuit community, CHEP recommendations on sodium intake, cancer and pre-cancer of the anus, the dangers of floppy eyelid syndrome, grief's extraordinary power, ethical approval for studies involving human participants, and more. Full issue table of contents: http://www.cmaj.ca/content/187/2.toc