SHR # 2071 :: Pregnenolone the Progenitor Hormone :: Dr. John Crisler - This show originally aired in 2009 but it was time to rerun it axs many of the discussion about HCG with Dr. Crisler brought us back to the steroid hormone pathways. Pregnenolone is domino 1 in that cascade since its direct precursor is cholesterol. If you don't know about pregnenolone you need to listen to this very thorough interview. You may want to start taking some yourself after you hear it. ::