Ajay Bisaria joined the Indian Foreign Service in 1987 and, in a career spanning thirty-five years, dealt with some of India's key economic and security relationships. He served as Indian high commissioner to Pakistan from 2017 to 2020. He has been Indian high commissioner to Canada (2020-22), and India's ambassador to Poland and Lithuania (2015-17).

He has also represented the country at the World Bank in Washington DC and in embassies in Berlin and Moscow. He has served in various capacities in the Ministry of External Affairs, Department of Commerce, and the Prime Minister's Office, where he was a key aide to Prime Minister Vajpayee from 1999 to 2004.

He has a Bachelor's Degree in Economics from St Stephen's College, Delhi University, an MBA from IIM Calcutta, and a Master's Degree in Public Policy from Princeton University.