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In the face of mounting concerns, Moderna says its vaccine is effective against multiple COVID-19 variants, but adds it will develop a "booster shot." Wealthy people are calling doctors' offices, offering vast sums for a shot. And a government watchdog will investigate whether a DOJ official tried to overturn election results.

Doctors worry that new variants of COVID-19 are sweeping through populations even faster than the original. President Biden is set to sign new executive orders that will impact the American economy and the military. And Republicans reckon with Donald Trump, his voters, and a potential new political party.

Doctors worry that new variants of COVID-19 are sweeping through populations even faster than the original. President Biden is set to sign new executive orders that will impact the American economy and the military. And Republicans reckon with Donald Trump, his voters, and a potential new political party.

President Biden dedicates his first full day in office to fighting COVID-19. Senate Republicans seek to delay a trial of President Trump. And experts say believers in debunked "Q Anon" conspiracy theories could move on to even more dangerous communities.

President Biden dedicates his first full day in office to fighting COVID-19. Senate Republicans seek to delay a trial of President Trump. And experts say believers in debunked "Q Anon" conspiracy theories could move on to even more dangerous communities.

In an unprecedented inauguration ceremony, Joseph R. Biden, Jr. becomes the 46th president of the United States. In a special edition of Start Here, ABC's team of reporters take you inside the moments that made Wednesday so important.

In an unprecedented inauguration ceremony, Joseph R. Biden, Jr. becomes the 46th president of the United States. In a special edition of Start Here, ABC's team of reporters take you inside the moments that made Wednesday so important.

Ahead of President-Elect Joe Biden's inauguration, two voters describe what they'd like to hear as he takes office. Senate Majority Leader Mitch McConnell escalates the battle against President Trump, but legislative battles are just getting started. And presidential historian Mark Updegrove previews Biden's speech.

Ahead of President-Elect Joe Biden's inauguration, two voters describe what they'd like to hear as he takes office. Senate Majority Leader Mitch McConnell escalates the battle against President Trump, but legislative battles are just getting started. And presidential historian Mark Updegrove previews Biden's speech.

President Trump prepares to exit the White House. Washington goes into its most severe lockdown in decades. And as American coronavirus deaths reach 400,000, scientists ponder what 2021 will look like.