Systemic lupus erythematosus (SLE, or lupus) is a systemic autoimmune disease that occurs when the body attacks its own tissues and organs. The severity of symptoms of SLE range from mild to severe and even wax and wane within a single patient, making the course unpredictable. In this AudioBrick, we'll discuss the basic features of the disease before exploring its etiology, diagnosis, and management.

After listening to this AudioBrick, you should be able to:

Define systemic lupus erythematosus (SLE) and describe its major clinical manifestations.

Describe the pathogenesis of SLE

Describe the spectrum of autoantibodies in SLE and which are most diagnostic

Describe the typical clinical course of SLE and describe the treatment options available

You can also check out the original brick from our Immunology collection, which is available for free.

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