If early results hold up, GLP-1 drugs could take out a big bite out of vice and transform life as we know it. Maybe, suggests Bradley, we won't need nearly so many liquor and weed shops, fast-food joints, prisons, rehab facilities or casinos. But what will we all do instead? Plus, Bradley raves about self-driving taxis in Phoenix, reviews the ups and downs of a family vacation in Japan (up: making a TikTok video with Abby; down: horse sashimi), and argues for freeing the art market from all legal niceties and letting it run wild.

This episode was taped at P&T Knitwear at 180 Orchard Street — New York City’s only free podcast recording studio.

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